2003
Re: Evaluation of acute candesartan cilexetil therapy in stroke survivors.
Kernan WN. Re: Evaluation of acute candesartan cilexetil therapy in stroke survivors. Stroke 2003, 34: e237-8; author reply e237-8. PMID: 14631078, DOI: 10.1161/01.str.0000104158.59498.bc.Peer-Reviewed Original Research
1999
Stratified Randomization for Clinical Trials
Kernan W, Viscoli C, Makuch R, Brass L, Horwitz R. Stratified Randomization for Clinical Trials. Journal Of Clinical Epidemiology 1999, 52: 19-26. PMID: 9973070, DOI: 10.1016/s0895-4356(98)00138-3.Peer-Reviewed Original ResearchConceptsStratified randomizationSmall trialsInterim analysisActive-control equivalence trialsClinical factorsLarge trialsSuperiority trialSubgroup analysisClinical trialsTreatment responsivenessTreatment outcomesMEDLINE searchTreatment groupsStratification factorsEquivalence trialPrognosisTrialsRandomizationType ITheoretical benefitsImportance of stratificationStratificationSample sizeInvestigatorsPatients