Paradoxical Prefrontal–Amygdala Recruitment to Angry and Happy Expressions in Pediatric Posttraumatic Stress Disorder
Keding TJ, Herringa RJ. Paradoxical Prefrontal–Amygdala Recruitment to Angry and Happy Expressions in Pediatric Posttraumatic Stress Disorder. Neuropsychopharmacology 2016, 41: 2903-2912. PMID: 27329685, PMCID: PMC5061882, DOI: 10.1038/npp.2016.104.Peer-Reviewed Original ResearchConceptsPediatric posttraumatic stress disorderPediatric PTSDPosttraumatic stress disorderAngry facesPTSD youthHappy facesMedial prefrontal cortexHealthy youthEmotional facesEmotional expressionStress disorderCross-sectional age-related differencesImplicit emotional faceThreat-related emotionsPositive emotional expressionEmotion processing circuitryTrauma-related psychopathologyEmotional faces taskAbnormal neural responsesPrefrontal-amygdala circuitsWhole-brain analysisAmygdala/hippocampusAge-related differencesAge-related findingsEmotion interaction