Synchronization and desynchronization in epilepsy: controversies and hypotheses
Jiruska P, de Curtis M, Jefferys J, Schevon C, Schiff S, Schindler K. Synchronization and desynchronization in epilepsy: controversies and hypotheses. The Journal Of Physiology 2013, 591: 787-797. PMID: 23184516, PMCID: PMC3591697, DOI: 10.1113/jphysiol.2012.239590.Peer-Reviewed Original ResearchConceptsNeuronal firingPathophysiology of epilepsyFunctional brain disordersEnd of seizureEpileptiform phenomenaLocal field potentialsLarge neuronal populationsNeuronal populationsNon-firing neuronsBrain disordersSeizuresSpecific inhibitoryEpilepsyExcitatory interactionsNeuronal networksRecent evidenceField potentialsHypersynchronous statesExcessive synchronizationFiring