Arteriovenous fistula-induced cardiac remodeling shows cardioprotective features in mice
Lee SR, Thorn S, Guerrera N, Gonzalez L, Taniguchi R, Langford J, Sinusas AJ, Dardik A. Arteriovenous fistula-induced cardiac remodeling shows cardioprotective features in mice. JVS Vascular Science 2021, 2: 110-128. PMID: 34423320, PMCID: PMC8375600, DOI: 10.1016/j.jvssci.2021.05.002.Peer-Reviewed Original ResearchArteriovenous fistulaCardiac hypertrophyCardioprotective featuresRelative LV wall thicknessPoor cardiac outcomesRight heart functionSham-operated miceAdaptive cardiac hypertrophyLV wall thicknessSignificant sex-dependent differencesAreas of fibrosisInflammation-related genesPhysiologic cardiac hypertrophyCardiac chamber sizeCardiac fetal genesWild-type miceSex-dependent differencesSimilar body weightIngenuity Pathway AnalysisArrhythmogenic featuresAVF miceSerial echocardiographyCardiac outcomesDiastolic functionLV systolic