Phosphofructokinase relocalizes into subcellular compartments with liquid-like properties in vivo
Jang S, Xuan Z, Lagoy RC, Jawerth LM, Gonzalez IJ, Singh M, Prashad S, Kim HS, Patel A, Albrecht DR, Hyman AA, Colón-Ramos DA. Phosphofructokinase relocalizes into subcellular compartments with liquid-like properties in vivo. Biophysical Journal 2020, 120: 1170-1186. PMID: 32853565, PMCID: PMC8059094, DOI: 10.1016/j.bpj.2020.08.002.Peer-Reviewed Original ResearchConceptsSubcellular compartmentsDynamic subcellular localizationPhase-separated condensatesNormoxic conditions resultsLiquid-like propertiesCaenorhabditis elegansCryptochrome 2Subcellular localizationBiochemical regulationEnergy stressGlycolytic enzymesInternal molecular rearrangementsVivoCompartmentsElegansLocalizesSubcompartmentsMolecular rearrangementSpheroid shapeEnzymeRegulationPFKPhosphofructokinaseRecruitmentConditions results