2015
Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease: A Multicenter, Prospective Cohort Study
Pietrzak RH, Lim YY, Neumeister A, Ames D, Ellis KA, Harrington K, Lautenschlager NT, Restrepo C, Martins RN, Masters CL, Villemagne VL, Rowe CC, Maruff P. Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease: A Multicenter, Prospective Cohort Study. JAMA Psychiatry 2015, 72: 284-291. PMID: 25629787, DOI: 10.1001/jamapsychiatry.2014.2476.Peer-Reviewed Original ResearchConceptsPreclinical Alzheimer's diseaseSubjective memory complaintsElevated anxiety symptomsVerbal memoryExecutive functionGlobal cognitionAnxiety symptomsCognitive declineCognitive changesMemory complaintsAβ statusDepressive symptomsLow anxiety groupComprehensive neuropsychological evaluationHigh anxiety groupRole of anxietyFlorbetapir F 18Visual memoryCognitive domainsVisuospatial abilitiesMild cognitive impairmentNeuropsychological evaluationCognitive functionProspective cohort studyMore rapid decline
2008
Trait impulsiveness and executive function in healthy young adults
Pietrzak R, Sprague A, Snyder P. Trait impulsiveness and executive function in healthy young adults. Journal Of Research In Personality 2008, 42: 1347-1351. DOI: 10.1016/j.jrp.2008.03.004.Peer-Reviewed Original ResearchHealthy young adultsTrait impulsivenessPerformance-based neuropsychological testsNon-planning impulsiveness scoreTotal BIS-11 scoreMeasures of planningBarratt Impulsiveness Scale-11Executive function testsYoung adultsBIS-11 scoresCognitive complexityExecutive functionNeuropsychological testsImpulsiveness scoresConvergent validityImpulsivenessSpecific dimensionsMaze testMeasuresAdultsScoresPerformanceDimensionsValidityTest