2001
Interobserver reproducibility of Gleason grading of prostatic carcinoma: Urologic pathologists
Allsbrook W, Mangold K, Johnson M, Lane R, Lane C, Amin M, Bostwick D, Humphrey P, Jones E, Reuter V, Sakr W, Sesterhenn I, Troncoso P, Wheeler T, Epstein J. Interobserver reproducibility of Gleason grading of prostatic carcinoma: Urologic pathologists. Human Pathology 2001, 32: 74-80. PMID: 11172298, DOI: 10.1053/hupa.2001.21134.Peer-Reviewed Original ResearchConceptsUrologic pathologistsProstatic carcinomaInterobserver reproducibilityGleason scoreGleason gradingGleason grade groupLow-grade tumorsCribriform proliferationNeedle biopsyGroup 2Gleason patternGrading systemCarcinomaGrade groupTumorsPathologistsScoresGradingKappa coefficientBiopsyHistologyCoefficient kappa
1998
Predicting the pathology results of radical prostatectomy from preoperative information
Vollmer R, Keetch D, Humphrey P. Predicting the pathology results of radical prostatectomy from preoperative information. Cancer 1998, 83: 1567-1580. PMID: 9781951, DOI: 10.1002/(sici)1097-0142(19981015)83:8<1567::aid-cncr12>3.0.co;2-e.Peer-Reviewed Original ResearchConceptsRadical prostatectomyPreoperative informationNeedle biopsyTumor volumeStatistical methodsWashington University Medical CenterAdvanced tumor stageProstate-specific antigenUniversity Medical CenterPreoperative variablesSerum PSATumor stagePathology resultsPathology outcomesMedical CenterProstate carcinomaSpecific antigenProstatectomyLogistic regressionBinary outcomesMultivariate modelProbabilityOutcomesBiopsyObserved probability
1996
Repeat Biopsy Strategy in Men with Isolated Prostatic Intraepithelial Neoplasia on Prostate Needle Biopsy
Shepherd D, Keetch D, Humphrey P, Smith D, Stahl D. Repeat Biopsy Strategy in Men with Isolated Prostatic Intraepithelial Neoplasia on Prostate Needle Biopsy. Journal Of Urology 1996, 156: 460-463. DOI: 10.1016/s0022-5347(01)65881-6.Peer-Reviewed Original ResearchConceptsHigh-grade prostatic intraepithelial neoplasiaGrade prostatic intraepithelial neoplasiaProstatic intraepithelial neoplasiaIntraepithelial neoplasiaRepeat biopsyNeedle biopsyBiopsy techniqueSide of cancerProstate needle biopsyLocation of cancerPercent of casesInitial biopsySystematic biopsyMen 31Biopsy strategyBiopsyNeoplasiaCancerProstateQuadrant locationPatientsStrongest predictorMenSame sideMalignancyRepeat biopsy strategy in men with isolated prostatic intraepithelial neoplasia on prostate needle biopsy.
Shepherd D, Keetch D, Humphrey P, Smith D, Stahl D. Repeat biopsy strategy in men with isolated prostatic intraepithelial neoplasia on prostate needle biopsy. Journal Of Urology 1996, 156: 460-2; discussion 462-3. PMID: 8683703, DOI: 10.1097/00005392-199608000-00038.Peer-Reviewed Original ResearchConceptsHigh-grade prostatic intraepithelial neoplasiaGrade prostatic intraepithelial neoplasiaProstatic intraepithelial neoplasiaIntraepithelial neoplasiaRepeat biopsyNeedle biopsyBiopsy techniqueSide of cancerProstate needle biopsyLocation of cancerInitial biopsySystematic biopsyMen 31Biopsy strategyBiopsyNeoplasiaCancerProstateQuadrant locationStrongest predictorPatientsMenSame sideMalignancyDisease
1995
Interobserver Reproducibility in the Diagnosis of Prostatic Intraepithelial Neoplasia
Epstein J, Grignon D, Humphrey P, McNeal J, Sesterhenn I, Troncoso P, Wheeler T. Interobserver Reproducibility in the Diagnosis of Prostatic Intraepithelial Neoplasia. The American Journal Of Surgical Pathology 1995, 19: 873-886. PMID: 7611534, DOI: 10.1097/00000478-199508000-00002.Peer-Reviewed Original ResearchConceptsHigh-grade PINLow-grade PINInterobserver reproducibilityProstatic intraepithelial neoplasiaSmall atypical glandsBenign prostate tissueIntraepithelial neoplasiaSame histologyAtypical glandsBiopsy materialProminent nucleoliUniform diagnosisCribriform glandsProstate tissueCancerLesionsLevel of agreementDiagnostic issuesUniform agreementPathologistsGlandDiagnosisConsecutive examplesBiopsyGroup
1992
Immunoreactive Prostatic Specific Antigen in Male Periurethral Glands
Frazier H, Humphrey P, Burchette J, Paulson D. Immunoreactive Prostatic Specific Antigen in Male Periurethral Glands. Journal Of Urology 1992, 147: 246-248. PMID: 1370330, DOI: 10.1016/s0022-5347(17)37206-3.Peer-Reviewed Original ResearchConceptsProstatic specific antigenProstatic acid phosphatasePeriurethral glandsSpecific antigenUrethral specimensMalignant prostatic tissueMale urethral specimensAutopsy seriesUrethral biopsyProstatic cancerAntigen uniqueAutopsy specimensProstatic tissueStrong immunostainingHeterogenous stainingAntigenAcid phosphataseRecent evidenceGlandTissueBiopsyEvidencePatientsCancerImmunostaining