2017
Mixture Modeling of 2-D Gel Electrophoresis Spots Enhances the Performance of Spot Detection
Marczyk M. Mixture Modeling of 2-D Gel Electrophoresis Spots Enhances the Performance of Spot Detection. IEEE Transactions On NanoBioscience 2017, 16: 91-99. PMID: 28278480, DOI: 10.1109/tnb.2017.2676725.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsElectrophoresis, Gel, Two-DimensionalImage Processing, Computer-AssistedModels, TheoreticalNormal DistributionSoftware
2013
Adaptive filtering of microarray gene expression data based on Gaussian mixture decomposition
Marczyk M, Jaksik R, Polanski A, Polanska J. Adaptive filtering of microarray gene expression data based on Gaussian mixture decomposition. BMC Bioinformatics 2013, 14: 101. PMID: 23510016, PMCID: PMC3637832, DOI: 10.1186/1471-2105-14-101.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnimalsGene Expression ProfilingHumansNormal DistributionOligonucleotide Array Sequence AnalysisConceptsGaussian mixture decompositionFalse discoveriesMicroarray gene expression dataNon-informative genesAdaptive filteringSample meanAdaptive methodSample varianceGaussian componentsMixture decompositionGene filteringEarlier paperGene expression dataFilteringOptimal threshold valuePrevious methodsMicroarray experimentsNew methodTwo-step procedureThreshold valueCorrection methodPower of detectionImportant parametersSecond stepMicroarray data