A Chimeric RNA Characteristic of Rhabdomyosarcoma in Normal Myogenesis Process
Yuan H, Qin F, Movassagh M, Park H, Golden W, Xie Z, Zhang P, Sklar J, Li H. A Chimeric RNA Characteristic of Rhabdomyosarcoma in Normal Myogenesis Process. Cancer Discovery 2013, 3: 1394-1403. PMID: 24089019, DOI: 10.1158/2159-8290.cd-13-0186.Peer-Reviewed Original ResearchMeSH KeywordsCell DifferentiationCell LineForkhead Box Protein O1Forkhead Transcription FactorsGene Expression Regulation, DevelopmentalGene FusionHumansMesenchymal Stem CellsMuscle DevelopmentMusclesMyoD ProteinMyogeninOncogene Proteins, FusionPaired Box Transcription FactorsPAX3 Transcription FactorRhabdomyosarcoma, AlveolarTranslocation, GeneticConceptsPAX3-FOXO1Chimeric RNAsChromosomal translocationsMuscle differentiation processChimeric fusion RNAsChimeric gene productsNormal cellsNormal non-cancer cellsPluripotent cellsNormal fetal muscleNon-cancer cellsGene productsChromosomal rearrangementsPosttranscriptional mechanismsDevelopmental roleFusion RNAGene fusionsDifferentiation processRNA characteristicsSame lineageMyogenesis processChimeric productsNormal developmentRhabdomyosarcoma cellsRNA