2019
Sensitive detection of EBV microRNAs across cancer spectrum reveals association with decreased survival in adult acute myelocytic leukemia
Movassagh M, Oduor C, Forconi C, Moormann A, Bailey J. Sensitive detection of EBV microRNAs across cancer spectrum reveals association with decreased survival in adult acute myelocytic leukemia. Scientific Reports 2019, 9: 20321. PMID: 31889055, PMCID: PMC6937232, DOI: 10.1038/s41598-019-56472-1.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusEBV positivityEBV microRNAsAdult acute myeloid leukemia patientsAdult acute myelocytic leukemiaAcute myeloid leukemia patientsIndependent risk factorMyeloid leukemia patientsAcute myelocytic leukemiaPoor patient outcomesSpectrum of cancersMessenger RNAAdult patientsClinical outcomesBarr virusImmune impairmentAML tumorsRisk factorsPatient outcomesLeukemia patientsPediatric AMLMyelocytic leukemiaPrognostic biomarkerCancer spectrumNumerous human cancers
2017
Human and Epstein-Barr Virus miRNA Profiling as Predictive Biomarkers for Endemic Burkitt Lymphoma
Oduor C, Movassagh M, Kaymaz Y, Chelimo K, Otieno J, Ong'echa J, Moormann A, Bailey J. Human and Epstein-Barr Virus miRNA Profiling as Predictive Biomarkers for Endemic Burkitt Lymphoma. Frontiers In Microbiology 2017, 8: 501. PMID: 28400759, PMCID: PMC5368269, DOI: 10.3389/fmicb.2017.00501.Peer-Reviewed Original ResearchEndemic Burkitt lymphomaEpstein-Barr virusEBV miRNAsPredictive biomarkersPatient outcomesBurkitt's lymphomaAggressive B-cell lymphomasInitial patient outcomesB-cell lymphomaPatient tumor samplesTumor resilienceTumor cell survivalClinical presentationJaw tumorsPoor outcomeDisease progressionAnatomical presentationCell lymphomaSignificant associationEvasion of apoptosisMYC proto-oncogeneTumor samplesMiR-10aTarget genesLymphoma