2021
ASO Author Reflections: Accurately Predicting Nodal pCR Holds the Key to Axillary Surgery De-escalation Strategies
Weiss A, Golshan M, Ollila DW. ASO Author Reflections: Accurately Predicting Nodal pCR Holds the Key to Axillary Surgery De-escalation Strategies. Annals Of Surgical Oncology 2021, 28: 5972-5973. PMID: 33851312, DOI: 10.1245/s10434-021-09953-5.Peer-Reviewed Original ResearchFactors Associated with Nodal Pathologic Complete Response Among Breast Cancer Patients Treated with Neoadjuvant Chemotherapy: Results of CALGB 40601 (HER2+) and 40603 (Triple-Negative) (Alliance)
Weiss A, Campbell J, Ballman KV, Sikov WM, Carey LA, Hwang ES, Poppe MM, Partridge AH, Ollila DW, Golshan M. Factors Associated with Nodal Pathologic Complete Response Among Breast Cancer Patients Treated with Neoadjuvant Chemotherapy: Results of CALGB 40601 (HER2+) and 40603 (Triple-Negative) (Alliance). Annals Of Surgical Oncology 2021, 28: 5960-5971. PMID: 33821344, PMCID: PMC8532250, DOI: 10.1245/s10434-021-09897-w.Peer-Reviewed Original ResearchConceptsBreast pathologic complete responsePathologic complete responseResidual breast diseaseTriple-negative breast cancerNodal pathologic complete responsePretreatment nodal statusClinical nodal statusNeoadjuvant chemotherapyNodal statusAxillary surgeryComplete responseCALGB 40601YpN0 rateAxillary nodal involvementResidual nodal diseaseProportion of patientsCareful patient selectionBreast cancer patientsNAC regimensYpN0 diseaseYpN0 statusCN0 patientsNodal diseaseNodal involvementMultivariable analysis
2020
Omission of Surgical Axillary Lymph Node Staging in Patients with Tubular Breast Cancer
Özkurt E, Wong S, Rhei E, Golshan M, Brock J, Barbie TU. Omission of Surgical Axillary Lymph Node Staging in Patients with Tubular Breast Cancer. Annals Of Surgical Oncology 2020, 28: 2589-2598. PMID: 33078312, DOI: 10.1245/s10434-020-09223-w.Peer-Reviewed Original ResearchConceptsInvasive ductal carcinomaER-positive invasive ductal carcinomasSurgical axillary stagingNational Cancer DatabaseTubular carcinomaLN involvementAxillary stagingOverall survivalDuctal carcinomaGrade IBreast cancerPositive invasive ductal carcinomaAxillary lymph node stagingKaplan-Meier survival curvesAxillary LN involvementFavorable breast cancerLN-positive diseasePropensity-matched analysisKaplan-Meier methodLymph node metastasisLymph node stagingTubular breast cancerLN diseaseNCDB cohortNodal involvement
2016
Breast conservation following neoadjuvant therapy for breast cancer in the modern era: Are we losing the opportunity?
Criscitiello C, Curigliano G, Burstein H, Wong S, Esposito A, Viale G, Giuliano M, Veronesi U, Santangelo M, Golshan M. Breast conservation following neoadjuvant therapy for breast cancer in the modern era: Are we losing the opportunity? European Journal Of Surgical Oncology 2016, 42: 1780-1786. PMID: 27825710, DOI: 10.1016/j.ejso.2016.10.011.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsAxillaBreast NeoplasmsClinical Decision-MakingFemaleGenes, BRCA1Genes, BRCA2Genetic Predisposition to DiseaseHereditary Breast and Ovarian Cancer SyndromeHumansLymph Node ExcisionMastectomyMastectomy, SegmentalMedical OveruseNeoadjuvant TherapyPatient PreferenceSurgical OncologyConceptsBreast conservationNeoadjuvant therapyBreast cancerSystemic therapyPathologic complete response rateComplete response rateBreast conservation ratesEffective systemic treatmentPatient-level variablesInvasive surgical approachNeoadjuvant trialsInoperable patientsSurgical overtreatmentSystemic treatmentSurgical approachSurgical benefitsOncology communityResponse ratePatientsTherapyCancerAggressive optionsMastectomySurgeonsConservation rate
2010
Can axillary lymph node dissection be omitted in patients with breast cancer and positive sentinel nodes?
Dominici L, Golshan M. Can axillary lymph node dissection be omitted in patients with breast cancer and positive sentinel nodes? Minerva Surgery 2010, 65: 547-54. PMID: 21081866.Peer-Reviewed Original ResearchConceptsBreast cancerSentinel lymphAxillary lymph node dissectionPositive sentinel lymph nodesCompletion axillary dissectionLymph node dissectionPositive axillary nodesPositive sentinel nodesSentinel lymph nodesStandard of careInvasive surgical managementNegative axillaAxillary dissectionAxillary lymphNode dissectionAxillary nodesLymph nodesSentinel nodesSurgical managementSurgical proceduresPatientsLymphCancerDissectionTherapeutic purposes