Epigenetic targeting in breast cancer: therapeutic impact and future direction.
Lustberg M, Ramaswamy B. Epigenetic targeting in breast cancer: therapeutic impact and future direction. Drug News & Perspectives 2009, 22: 369-81. PMID: 19890494, PMCID: PMC3658161, DOI: 10.1358/dnp.2009.22.7.1405072.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic AgentsBreast NeoplasmsEnzyme InhibitorsEpigenesis, GeneticFemaleHistone Deacetylase InhibitorsHumansRandomized Controlled Trials as TopicConceptsEpigenetic changesHistone modificationsHistone deacetylase inhibitorsGene expressionMajor epigenetic changesHeritable changesRepressor complexDNA methylationGene sequencesEpigenetic targetingDeacetylase inhibitorsMultistep processMethylationExpressionEpigeneticsBreast carcinogenesisGenesReversible processAntiapoptosisNovel therapiesSequenceInvasionProliferationTargetingBreast cancer