Effects of Omega-3 Fatty Acids on Insulin Resistance in an Ovariectomized Mouse Model of Diet-Induced Obesity Treated with Chemotherapy
Ormiston K, Zhang Z, Murphy K, DeVries A, Lustberg M, Andridge R, Orchard T. Effects of Omega-3 Fatty Acids on Insulin Resistance in an Ovariectomized Mouse Model of Diet-Induced Obesity Treated with Chemotherapy. Current Developments In Nutrition 2020, 4: nzaa044_044. PMCID: PMC7257328, DOI: 10.1093/cdn/nzaa044_044.Peer-Reviewed Original ResearchInsulin resistanceLF groupBody weightBlood glucoseHF dietHF groupBody fatHigh-fat diet-induced insulin resistanceOmega-3 fatty acidsDiet-induced insulin resistanceLF diet groupHomeostatic model assessmentHOMA-IR scoreDiet-Induced ObesityOvariectomized mouse modelDiet-fed miceLow-fat dietHigh-fat dietLower body weightPercent body fatFasted blood glucoseLower scoresChemotherapy injectionsConclusion ChemotherapySerum insulin