2018
Low Sucrose, Omega-3 Enriched Diet Has Region-Specific Effects on Neuroinflammation and Synaptic Function Markers in a Mouse Model of Doxorubicin-Based Chemotherapy
Orchard T, Gaudier-Diaz M, Phuwamongkolwiwat-Chu P, Andridge R, Lustberg M, Bomser J, Cole R, Belury M, DeVries A. Low Sucrose, Omega-3 Enriched Diet Has Region-Specific Effects on Neuroinflammation and Synaptic Function Markers in a Mouse Model of Doxorubicin-Based Chemotherapy. Nutrients 2018, 10: 2004. PMID: 30567351, PMCID: PMC6316589, DOI: 10.3390/nu10122004.Peer-Reviewed Original ResearchConceptsDHA dietSynaptic damageSecond injectionPro-inflammatory cytokines IL-1βChemotherapy-treated miceKC/GROCytokines IL-1βLong-term brainLow-sucrose dietTwo-injection regimenQuality of lifeSpecific brain regionsBrain DHARegion-specific effectsC57BL/6 miceCancer survivorsFunction markersIL-1βIL-6Synaptic markersIL-5Mouse modelNeuroinflammationSucrose dietChemotherapy
2015
Effects of Sucrose and Omega-3 Fatty Acids on Chemotherapy-Induced Neuroinflammation in a Mouse Model of Breast Cancer
Gaudier-Diaz M, Lustberg M, Cole R, Belury M, DeVries A, Orchard T. Effects of Sucrose and Omega-3 Fatty Acids on Chemotherapy-Induced Neuroinflammation in a Mouse Model of Breast Cancer. Journal Of The Academy Of Nutrition And Dietetics 2015, 115: a25. DOI: 10.1016/j.jand.2015.06.081.Peer-Reviewed Original Research