Sensorimotor Cortical Thickness Changes Following Taxane-Based Chemotherapy: Support for a CNS Role in CIPN?
Worthen-Chaudhari L, Monfort S, Chaudhari A, Lustberg M. Sensorimotor Cortical Thickness Changes Following Taxane-Based Chemotherapy: Support for a CNS Role in CIPN? Archives Of Physical Medicine And Rehabilitation 2023, 104: e51. DOI: 10.1016/j.apmr.2022.12.148.Peer-Reviewed Original ResearchChemotherapy cyclesCortical thicknessBrain changesBreast cancerSensorimotor regionsCycles of TaxolSensorimotor cortical thicknessChemotherapy-induced neuropathyFirst chemotherapy cycleBreast cancer survivorsMain outcome measuresMean cortical thicknessSensory-motor regionsBrain structural integrityTaxane exposureChemotherapy exposureCancer survivorsCentral effectsChemotherapy treatmentDesign ProspectiveOutpatient oncologyCNS roleCommencement of studyOutcome measuresGait variability