2023
Prevalence of targetable genomic alterations in young women with advanced breast cancer: a cross-sectional study
Blansky D, Ansari N, Gao L, Sokol E, Sivakumar S, Huang R, Pelletier M, Levy M, Pavlick D, Danziger N, Ross J, Lustberg M, Rozenblit M. Prevalence of targetable genomic alterations in young women with advanced breast cancer: a cross-sectional study. Breast Cancer Research And Treatment 2023, 204: 181-185. PMID: 37999916, DOI: 10.1007/s10549-023-07179-5.Peer-Reviewed Original ResearchComprehensive genomic profilingBreast cancerYoung womenGenomic alterationsAdvanced breast cancerPD-L1 expressionTargetable genomic alterationsWorse clinical outcomesTime of diagnosisTumor mutational burdenCross-sectional studyBreast cancer casesFoundation MedicineClinical outcomesPIK3CA mutationsCancer casesEstrogen receptorMutational burdenOlder womenConclusionOur findingsTotal casesBreast tumorsTumor tissueBRCA1 mutationsMicrosatellite instability
2011
PD10-01: Prevalence of Dysfunctional Fanconi Anemia (FA) DNA Repair Pathway in Breast Cancer.
Ramaswamy B, Srividya V, Mullins D, Carothers S, Young G, Wenrui D, Zhao W, Lustberg M, Leon M, Weslowski R, Layman R, Mrozek E, Shapiro C, Villalona-Calero M. PD10-01: Prevalence of Dysfunctional Fanconi Anemia (FA) DNA Repair Pathway in Breast Cancer. Cancer Research 2011, 71: pd10-01-pd10-01. DOI: 10.1158/0008-5472.sabcs11-pd10-01.Peer-Reviewed Original ResearchDNA repair pathwaysFA defectRepair pathwaysFanconi anemia DNA repair pathwayFA DNA repair pathwayHormone receptorsAssociated gene productsRepair fociFA pathwayGene productsCellular responsesMolecular markersFA networkDNA damagePathway defectsPathwayImmuno-fluorescence testADP-ribose polymerase inhibitorsFunctional defectsCommon pathwayFluorescence microscopeMolecular subtypesBreast tumorsTumor cellsFANCD2