Evidence that estrogen directly and indirectly modulates C1 adrenergic bulbospinal neurons in the rostral ventrolateral medulla
Wang G, Drake C, Rozenblit M, Zhou P, Alves S, Herrick S, Hayashi S, Warrier S, Iadecola C, Milner T. Evidence that estrogen directly and indirectly modulates C1 adrenergic bulbospinal neurons in the rostral ventrolateral medulla. Brain Research 2006, 1094: 163-178. PMID: 16696957, DOI: 10.1016/j.brainres.2006.03.089.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood PressureDendritesDose-Response Relationship, DrugEfferent PathwaysEpinephrineEstradiolEstradiol CongenersEstrogen AntagonistsEstrogen Receptor alphaEstrogen Receptor betaEstrogensFemaleHypertensionMedulla OblongataMembrane PotentialsPatch-Clamp TechniquesPostmenopausePresynaptic TerminalsRatsRats, Sprague-DawleySpinal CordSympathetic Nervous SystemTyrosine 3-MonooxygenaseConceptsBlood pressure controlERalpha-irERbeta-irBulbospinal neuronsSympathetic toneCurrent inhibitionPressure controlRostral ventrolateral medulla (RVLM) regionWhole-cell patch-clamp recordingsBulbospinal RVLM neuronsER antagonist ICI182780ERalpha-selective agonistEstrogen receptor immunoreactivityRostral ventrolateral medullaC1 adrenergic neuronsEffects of estrogenPatch-clamp recordingsERbeta-selective agonistsC1 neuronsRVLM neuronsReceptor immunoreactivityVentrolateral medullaBlood pressureAdrenergic neuronsEstrogen effects