Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response
Dhingra N, Shemer A, da Rosa J, Rozenblit M, Fuentes-Duculan J, Gittler JK, Finney R, Czarnowicki T, Zheng X, Xu H, Estrada YD, Cardinale I, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E. Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response. Journal Of Allergy And Clinical Immunology 2014, 134: 362-372. PMID: 24768652, DOI: 10.1016/j.jaci.2014.03.009.Peer-Reviewed Original ResearchConceptsAllergic contact dermatitisHuman allergic contact dermatitisTh1/Th17Different allergensHigher immune activationMurine contact hypersensitivityStrong Th2 biasContact hypersensitivity modelCommon occupational diseaseT cell activationTh22 polarizationCommon allergensContact hypersensitivityTh2 biasDermatitis skinImmune activationClinical reactionsHypersensitivity modelImmune polarizationIndividual allergensContact dermatitisImmune responseAllergen groupsInnate immunityOccupational diseases