2014
Diffusion Tensor Imaging as a Predictor of Locomotor Function after Experimental Spinal Cord Injury and Recovery
Kelley BJ, Harel NY, Kim CY, Papademetris X, Coman D, Wang X, Hasan O, Kaufman A, Globinsky R, Staib LH, Cafferty WB, Hyder F, Strittmatter SM. Diffusion Tensor Imaging as a Predictor of Locomotor Function after Experimental Spinal Cord Injury and Recovery. Journal Of Neurotrauma 2014, 31: 1362-1373. PMID: 24779685, PMCID: PMC4120934, DOI: 10.1089/neu.2013.3238.Peer-Reviewed Original ResearchConceptsSpinal cord injuryDiffusion tensor imagingCord injuryAxonal integrityLocomotor functionExperimental spinal cord injuryTraumatic spinal cord injuryFemale Sprague-Dawley ratsTensor imagingFractional anisotropyFunctional recovery assessmentSpinal cord contusionLimited functional recoveryLong-term disabilityQuantitative diffusion tensor imagingRodent SCI modelsSprague-Dawley ratsSpinal cord morphologyWhite matter pathologyCaudal spinal cordWhite matter integrityInjury epicenterMidthoracic laminectomyCord contusionPrimary outcome
2009
DTI abnormalities in anterior corpus callosum of rats with spike–wave epilepsy
Chahboune H, Mishra AM, DeSalvo MN, Staib LH, Purcaro M, Scheinost D, Papademetris X, Fyson SJ, Lorincz ML, Crunelli V, Hyder F, Blumenfeld H. DTI abnormalities in anterior corpus callosum of rats with spike–wave epilepsy. NeuroImage 2009, 47: 459-466. PMID: 19398019, PMCID: PMC2712639, DOI: 10.1016/j.neuroimage.2009.04.060.Peer-Reviewed Original ResearchConceptsSpike-wave dischargesDiffusion tensor imagingAnterior corpus callosumWAG/RijFractional anisotropyWhite matter pathwaysSeizure activityAbsence epilepsyCorpus callosumDTI abnormalitiesEpileptic WAG/Rij ratsWAG/Rij ratsGenetic Absence Epilepsy RatsCallosal fractional anisotropySomatosensory cortex regionSpike-wave epilepsyBilateral spike-wave dischargesCommon seizure disorderWistar albino Glaxo ratsGlaxo ratsChronic seizuresEpileptic animalsNonepileptic controlsSeizure disorderNeurological difficulties