Pathology of B cell and neutrophil infiltration in the YUMMER1.7 mouse model of spontaneous melanoma tumor regression
Blenman K, Wang J, Cowper S, Bosenberg M. Pathology of B cell and neutrophil infiltration in the YUMMER1.7 mouse model of spontaneous melanoma tumor regression. The Journal Of Immunology 2019, 202: 136.25-136.25. DOI: 10.4049/jimmunol.202.supp.136.25.Peer-Reviewed Original ResearchB cellsMelanoma cellsTumor regressionPlasmablasts/plasma cellsTumor-infiltrating B cellsLonger progression-free survivalMelanoma tumor regressionProgression-free survivalAdaptive immune responsesB cell numbersNeutrophil extracellular trapsNeutrophil infiltrationImmunotherapy treatmentSpontaneous regressionMetastatic melanomaAdverse reactionsGeographic necrosisImmune cellsNeutrophil responseHistological changesExtracellular trapsPlasma cellsImmune responseTherapy showTumor massPathology of spontaneous and immunotherapy‐induced tumor regression in a murine model of melanoma
Blenman KRM, Wang J, Cowper S, Bosenberg M. Pathology of spontaneous and immunotherapy‐induced tumor regression in a murine model of melanoma. Pigment Cell & Melanoma Research 2019, 32: 448-457. PMID: 30702217, PMCID: PMC6500596, DOI: 10.1111/pcmr.12769.Peer-Reviewed Original ResearchConceptsTumor regressionB cellsMelanoma cellsNeutrophil extracellular trapsNeutrophil countAdverse reactionsGeographic necrosisNeutrophil responseExtracellular trapsHistological changesPlasma cellsMurine modelHost responseTumor microenvironmentImmunotherapyNeutrophilsTumorsRegression modelsCellsRegressionLike formationImmunocompetentPlasmablastsEpithelioidMelanoma