1999
Identification of the RNA Binding Domain of T4 RegA Protein by Structure-based Mutagenesis*
Gordon J, Sengupta T, Phillips C, O'Malley S, Williams K, Spicer E. Identification of the RNA Binding Domain of T4 RegA Protein by Structure-based Mutagenesis*. Journal Of Biological Chemistry 1999, 274: 32265-32273. PMID: 10542265, DOI: 10.1074/jbc.274.45.32265.Peer-Reviewed Original ResearchConceptsRegA proteinBeta-sheet residuesGel mobility shift assaysRNA gel mobility shift assaysProtein-RNA interactionsMutagenesis of residuesRNA Binding DomainRNA binding siteMobility shift assaysRNA recognition propertiesBeta-sheet regionUnique structural motifMutant proteinsRNA bindingProtein foldsShift assaysBinding domainsMutagenesis studiesStructural domainsDomain IIMutagenesisEquilibrium binding assaysProteinRNABinding sites
1997
Crystal structure of the two RNA binding domains of human hnRNP A1 at 1.75 Å resolution
Shamoo Y, Krueger U, Rice L, Williams K, Steitz T. Crystal structure of the two RNA binding domains of human hnRNP A1 at 1.75 Å resolution. Nature Structural & Molecular Biology 1997, 4: 215-222. PMID: 9164463, DOI: 10.1038/nsb0397-215.Peer-Reviewed Original ResearchBinding SitesComputer SimulationCrystallography, X-RayHeterogeneous Nuclear Ribonucleoprotein A1Heterogeneous-Nuclear Ribonucleoprotein Group A-BHeterogeneous-Nuclear RibonucleoproteinsHumansModels, MolecularModels, StructuralProtein FoldingProtein Structure, SecondaryRibonucleoproteinsRNA SplicingRNA, Small NuclearRNA-Binding ProteinsSoftware
1993
Translational Repression by the Bacteriophage T4 Gene 32 Protein Involves Specific Recognition of an RNA Pseudoknot Structure
Shamoo Y, Tam A, Konigsberg W, Williams K. Translational Repression by the Bacteriophage T4 Gene 32 Protein Involves Specific Recognition of an RNA Pseudoknot Structure. Journal Of Molecular Biology 1993, 232: 89-104. PMID: 8331672, DOI: 10.1006/jmbi.1993.1372.Peer-Reviewed Original Research
1986
Protein chemistry‐nuclear magnetic resonance approach to mapping functional domains in single‐stranded DNA binding proteins
Coleman J, Williams K, King G, Prigodich R, Shamoo Y, Konigsberg W. Protein chemistry‐nuclear magnetic resonance approach to mapping functional domains in single‐stranded DNA binding proteins. Journal Of Cellular Biochemistry 1986, 32: 305-326. PMID: 3543031, DOI: 10.1002/jcb.240320407.Peer-Reviewed Original Research