1994
Both RNA-binding domains in heterogenous nuclear ribonucleoprotein A1 contribute toward single-stranded-RNA binding.
Shamoo Y, Abdul-Manan N, Patten A, Crawford J, Pellegrini M, Williams K. Both RNA-binding domains in heterogenous nuclear ribonucleoprotein A1 contribute toward single-stranded-RNA binding. Biochemistry 1994, 33: 8272-81. PMID: 7518244, DOI: 10.1021/bi00193a014.Peer-Reviewed Original ResearchAmino Acid SequenceBinding SitesCircular DichroismCloning, MolecularDNAElectrochemistryHeterogeneous Nuclear Ribonucleoprotein A1Heterogeneous-Nuclear Ribonucleoprotein Group A-BHeterogeneous-Nuclear RibonucleoproteinsHydrogen-Ion ConcentrationMolecular Sequence DataOligonucleotidesPeptide FragmentsPoly UProtein Structure, SecondaryRibonucleoproteinsRNASodium ChlorideThermodynamics
1992
Purification and characterization of an endo-exonuclease from adult flies of Drosophila melanogaster
Shuai K, Gupta C, Hawley R, Chase J, Stone K, Williams K. Purification and characterization of an endo-exonuclease from adult flies of Drosophila melanogaster. Nucleic Acids Research 1992, 20: 1379-1385. PMID: 1313969, PMCID: PMC312186, DOI: 10.1093/nar/20.6.1379.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAmino AcidsAnimalsChromatography, DEAE-CelluloseChromatography, High Pressure LiquidDNA, Single-StrandedDrosophila melanogasterElectrophoresis, Polyacrylamide GelEndonucleasesExonucleasesHot TemperatureHydrogen-Ion ConcentrationKineticsMolecular Sequence DataMolecular WeightSodium ChlorideSubstrate SpecificityUltracentrifugation
1986
Acidic lipids enhance cathepsin D cleavage of the myelin basic protein
Williams K, Williams N, Konigsberg W, Yu R. Acidic lipids enhance cathepsin D cleavage of the myelin basic protein. Journal Of Neuroscience Research 1986, 15: 137-145. PMID: 2421004, DOI: 10.1002/jnr.490150203.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainCathepsin DCattleEnzyme ActivationHydrogen-Ion ConcentrationHydrolysisKineticsMyelin Basic ProteinPhosphatidylinositolsSubstrate SpecificitySulfoglycosphingolipids
1982
Crystallization of a tryptic core of the single-stranded DNA binding protein of bacteriophage T4
McKay D, Williams K. Crystallization of a tryptic core of the single-stranded DNA binding protein of bacteriophage T4. Journal Of Molecular Biology 1982, 160: 659-661. PMID: 7175942, DOI: 10.1016/0022-2836(82)90321-7.Peer-Reviewed Original ResearchMeSH KeywordsCarrier ProteinsCrystallizationDNA, ViralHydrogen-Ion ConcentrationOsmolar ConcentrationT-PhagesTrypsin
1977
Kinetic mechanism of tRNA nucleotidyltransferase from Escherichia coli.
Williams K, Schofield P. Kinetic mechanism of tRNA nucleotidyltransferase from Escherichia coli. Journal Of Biological Chemistry 1977, 252: 5589-5597. PMID: 18468, DOI: 10.1016/s0021-9258(19)63391-0.Peer-Reviewed Original Research
1975
Evidence for metalloenzyme character of tRNA nucleotidyl transferase
Williams K, Schofield P. Evidence for metalloenzyme character of tRNA nucleotidyl transferase. Biochemical And Biophysical Research Communications 1975, 64: 262-267. PMID: 238508, DOI: 10.1016/0006-291x(75)90247-8.Peer-Reviewed Original Research