1985
Identification of a nucleic acid helix-destabilizing protein from rat liver as lactate dehydrogenase-5.
Williams K, Reddigari S, Patel G. Identification of a nucleic acid helix-destabilizing protein from rat liver as lactate dehydrogenase-5. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 5260-5264. PMID: 2991914, PMCID: PMC390547, DOI: 10.1073/pnas.82.16.5260.Peer-Reviewed Original ResearchConceptsHelix-destabilizing proteinSs-DNAAmino acid compositionHPLC tryptic peptide mapsNucleic acid helix-destabilizing proteinSolid-phase protein sequencingChemical modification studiesCoenzyme binding siteTyrosine-238Molecular weightSimilar amino acid compositionsTryptic peptide mapsAcid compositionLactate dehydrogenase 5Molecular homogeneitySimilar specific activitiesProtein sequencingLDH proteinDNA bindingAmino terminusBiological roleSingle proteinM chainTryptic peptidesVivo role
1979
Structural characteristics of interferons from mouse Ehrlich ascites tumor cells.
Cabrer B, Taira H, Broeze R, Kempe T, Williams K, Slattery E, Konigsberg W, Lengyel P. Structural characteristics of interferons from mouse Ehrlich ascites tumor cells. Journal Of Biological Chemistry 1979, 254: 3681-3684. PMID: 438151, DOI: 10.1016/s0021-9258(18)50635-9.Peer-Reviewed Original ResearchConceptsAmino acidsMouse EhrlichNH2-terminal amino acidsTryptic peptide mapsSmaller speciesLarger speciesPeptide mapsSpeciesTumor cellsSize classesNewcastle disease virusDisease virusSpecific activityCellsGlycosylationProteinUnits/AcidEhrlichCarboxypeptidaseInterferonIsolationStructural characteristics