Mitochondrial Redox Signaling and Tumor Progression
Chen Y, Zhang H, Zhou HJ, Ji W, Min W. Mitochondrial Redox Signaling and Tumor Progression. Cancers 2016, 8: 40. PMID: 27023612, PMCID: PMC4846849, DOI: 10.3390/cancers8040040.Peer-Reviewed Original ResearchMitochondrial redox proteinsExcessive ROSRedox proteinsCancer cellsMitochondrial redox signalingMitochondrial oxidative phosphorylationCellular ROS levelsStress signalingRedox regulationROS functionTumor progressionRedox signalingMitochondrial roleApoptotic signalingCancer cell proliferationRedox-sensitive pathwaysTranscriptional factorsReactive oxygen species generationTumor suppressorOxidative phosphorylationDNA mutationsOxygen species generationCancer progressionBasal ROSCancer invasion