2022
External validation of a model determining risk of neoplastic progression of Barrett’s esophagus in a cohort of U.S. veterans
Nguyen T, Thrift A, Ketwaroo G, Du X, Leon Novelo L, George R, Rosen D, El-Serag H. External validation of a model determining risk of neoplastic progression of Barrett’s esophagus in a cohort of U.S. veterans. Gastrointestinal Endoscopy 2022, 95: 1113-1122. PMID: 34998796, PMCID: PMC9119926, DOI: 10.1016/j.gie.2021.12.034.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaBarrett EsophagusDisease ProgressionEsophageal NeoplasmsHumansHyperplasiaPrecancerous ConditionsRetrospective StudiesRisk FactorsVeteransConceptsHigh-grade dysplasiaHigh-risk groupEsophageal adenocarcinomaBarrett's esophagusBE patientsDiscriminatory abilityHouston Veterans Affairs Medical CenterVeterans Affairs Medical CenterHGD/esophageal adenocarcinomaRetrospective cohort studyExternal validationExternal validation studyInitial EGDCohort studyConsecutive patientsSmoking statusDysplasia statusRisk groupsMedical CenterHigh riskGeneral populationNew diagnosisPatientsClinical practiceBiopsy sampling
2021
Prevalence and Predictors of Missed Dysplasia on Index Barrett’s Esophagus Diagnosing Endoscopy in a Veteran Population
Nguyen T, Thrift A, George R, Rosen D, El-Serag H, Ketwaroo G. Prevalence and Predictors of Missed Dysplasia on Index Barrett’s Esophagus Diagnosing Endoscopy in a Veteran Population. Clinical Gastroenterology And Hepatology 2021, 20: e876-e889. PMID: 33839273, PMCID: PMC8900254, DOI: 10.1016/j.cgh.2021.04.008.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaBarrett EsophagusDisease ProgressionEndoscopy, GastrointestinalEsophageal NeoplasmsHumansPrevalenceRetrospective StudiesVeteransConceptsBarrett's esophagusIndex esophagogastroduodenoscopyIndefinite dysplasiaBE diagnosisLong-segment Barrett's esophagusProportion of patientsSegment Barrett's esophagusDysplastic Barrett's esophagusLogistic regression modelsBE lengthDefinite dysplasiaHouston VANDBE patientsClose followInitial biopsyDysplasia surveillanceBE patientsEndoscopic samplingRisk factorsOdds ratioEsophagogastroduodenoscopyRetrospective analysisPatientsVeteran populationDysplasia
2020
Accuracy of a novel noninvasive secretin-enhanced MRCP severity index scoring system for diagnosis of chronic pancreatitis: correlation with EUS-based Rosemont criteria
Souza D, Alessandrino F, Ketwaroo G, Sawhney M, Mortele K. Accuracy of a novel noninvasive secretin-enhanced MRCP severity index scoring system for diagnosis of chronic pancreatitis: correlation with EUS-based Rosemont criteria. La Radiologia Medica 2020, 125: 816-826. PMID: 32266691, DOI: 10.1007/s11547-020-01181-3.Peer-Reviewed Original Research
2017
The Impact of Risk Factors of Chronic Pancreatitis on Secretin Pancreatic Function Testing
Kothari D, Ketwaroo G, Freedman S, Sheth S. The Impact of Risk Factors of Chronic Pancreatitis on Secretin Pancreatic Function Testing. Pancreas 2017, 46: 887-890. PMID: 28697128, DOI: 10.1097/mpa.0000000000000871.Peer-Reviewed Original ResearchConceptsRecurrent acute pancreatitisPeak bicarbonate concentrationHistory of APAcute pancreatitisRisk factorsPancreatic function testingChronic pancreatitisLocal complicationsFunction testingFemale sexBicarbonate concentrationRetrospective reviewUnivariate analysisFamily historyTobacco usePancreatitisPatientsMultivariate analysisAlcohol useComplicationsSignificant differencesSexFactorsHistory
2016
Localizing Acute Lower Gastrointestinal Hemorrhage: CT Angiography Versus Tagged RBC Scintigraphy.
Feuerstein J, Ketwaroo G, Tewani S, Cheesman A, Trivella J, Raptopoulos V, Leffler D. Localizing Acute Lower Gastrointestinal Hemorrhage: CT Angiography Versus Tagged RBC Scintigraphy. American Journal Of Roentgenology 2016, 207: 578-84. PMID: 27303989, DOI: 10.2214/ajr.15.15714.Peer-Reviewed Original ResearchConceptsAcute lower gastrointestinal bleedingLower gastrointestinal bleedingLower gastrointestinal hemorrhageCT angiographyRBC scintigraphyScintigraphic scansGastrointestinal bleedingGastrointestinal hemorrhageActive lower gastrointestinal bleedingAcute lower gastrointestinal hemorrhageUtility of CTAAcute kidney injuryBlood transfusion requirementsTertiary care hospitalAverage hospital lengthSite of bleedingActive gastrointestinal bleedingActive bleedingHospital lengthHospital mortalityKidney injuryTransfusion requirementsCare hospitalRetrospective reviewScintigraphic examination
2015
Salvage cryotherapy after failed radiofrequency ablation for Barrett’s esophagus–related dysplasia is safe and effective
Sengupta N, Ketwaroo G, Bak D, Kedar V, Chuttani R, Berzin T, Sawhney M, Pleskow D. Salvage cryotherapy after failed radiofrequency ablation for Barrett’s esophagus–related dysplasia is safe and effective. Gastrointestinal Endoscopy 2015, 82: 443-448. PMID: 25887715, DOI: 10.1016/j.gie.2015.01.033.Peer-Reviewed Original ResearchConceptsHigh-grade dysplasiaLow-grade dysplasiaRadiofrequency ablationIntramucosal carcinomaRecurrent dysplasiaEndoscopic therapyIntestinal metaplasiaBE dysplasiaEffective endoscopic therapyEradication of dysplasiaSafety of cryotherapyTertiary care centerBarrett's esophagus dysplasiaRFA sessionsSalvage cryotherapyCohort studySecondary outcomesHiatal herniaSingle centerInitial eradicationRetrospective natureEffective treatmentPatientsCryotherapyDysplasia
2013
Defining the Accuracy of Secretin Pancreatic Function Testing in Patients With Suspected Early Chronic Pancreatitis
Ketwaroo G, Brown A, Young B, Kheraj R, Sawhney M, Mortele K, Najarian R, Tewani S, Dasilva D, Freedman S, Sheth S. Defining the Accuracy of Secretin Pancreatic Function Testing in Patients With Suspected Early Chronic Pancreatitis. The American Journal Of Gastroenterology 2013, 108: 1360. PMID: 23711627, PMCID: PMC5388854, DOI: 10.1038/ajg.2013.148.Peer-Reviewed Original ResearchConceptsEarly chronic pancreatitisNegative predictive valueChronic pancreatitisPancreatic function testingPositive predictive valueHistologic evidenceFunction testingPredictive valuePancreatic imagingTertiary care institutionMedian followPositive patientsRetrospective reviewPancreatic functionMedical recordsPancreatitisPatientsDiagnostic accuracyCharacteristic symptomsCare institutionsFollowSubsequent developmentImagingEvidenceSymptoms