Inhibitory Effect of Pregnancy on Counterregulatory Hormone Responses to Hypoglycemia in Awake Rat
Rossi G, Lapaczewski P, Diamond M, Jacob R, Shulman G, Sherwin R. Inhibitory Effect of Pregnancy on Counterregulatory Hormone Responses to Hypoglycemia in Awake Rat. Diabetes 1993, 42: 1440-1445. PMID: 8375583, DOI: 10.2337/diab.42.10.1440.Peer-Reviewed Original ResearchConceptsPregnant ratsGlucagon responseNonpregnant controlsAwake pregnant ratsCounterregulatory hormone responsesIntensive insulin treatmentRelease of epinephrineHypoglycemia risk factorsHypoglycemic clamp studiesDiabetic pregnanciesGlucose counterregulationMaternal hypoglycemiaHypoglycemic stimulusEpinephrine releaseEpinephrine levelsMild hypoglycemiaBrisk responseNonfasting stateRisk factorsAwake ratsInsulin treatmentKetone levelsClamp studiesGlucose levelsNonfasted state