2016
Postoperative Radiation Therapy Is Associated with Longer Overall Survival in Completely Resected Stage II and III Thymoma—An Analysis of the International Thymic Malignancies Interest Group Retrospective Database
Rimner A, Yao X, Huang J, Antonicelli A, Ahmad U, Korst RJ, Detterbeck F, Gomez DR. Postoperative Radiation Therapy Is Associated with Longer Overall Survival in Completely Resected Stage II and III Thymoma—An Analysis of the International Thymic Malignancies Interest Group Retrospective Database. Journal Of Thoracic Oncology 2016, 11: 1785-1792. PMID: 27346413, PMCID: PMC5257334, DOI: 10.1016/j.jtho.2016.06.011.Peer-Reviewed Original ResearchConceptsPostoperative radiation therapyStage IIOS benefitRadiation therapyUse of PORTMasaoka-Koga stage IIInternational Thymic Malignancy Interest GroupStage II thymomaOverall survival benefitPrimary end pointMultivariate Cox modelLonger overall survivalLog-rank testIndividual patient dataImproved OSParaneoplastic syndromeOverall survivalSurvival benefitOS ratesHistologic subtypePatient populationRetrospective databaseUnivariate analysisCox modelThymoma
2015
Gender, Age, and Comorbidity Status Predict Improved Survival with Adjuvant Chemotherapy Following Lobectomy for Non-small Cell Lung Cancers Larger than 4 cm
Sandler BJ, Wang Z, Hancock JG, Boffa DJ, Detterbeck FC, Kim AW. Gender, Age, and Comorbidity Status Predict Improved Survival with Adjuvant Chemotherapy Following Lobectomy for Non-small Cell Lung Cancers Larger than 4 cm. Annals Of Surgical Oncology 2015, 23: 638-645. PMID: 26474557, DOI: 10.1245/s10434-015-4902-8.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAge FactorsAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellChemotherapy, AdjuvantCohort StudiesCombined Modality TherapyComorbidityFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMiddle AgedNeoplasm StagingPneumonectomyPrognosisSex FactorsSurvival RateYoung AdultConceptsNon-small cell lung cancerAdjuvant chemotherapyNational Cancer Data BaseNon-small cell lungCharlson-Deyo scorePretreatment prognostic factorsCell lung cancerCD scoresGroup of womenGroup of menConclusionsAdjuvant chemotherapySurvival benefitT2 tumorsPrognostic factorsDistant metastasisWomen 65Cell lungLung cancerNSCLC tumorsImproved outcomesChemotherapySurgeryPatientsWomenSurvivalResection of oligometastatic lung cancer to the pancreas may yield a survival benefit in select patients – A systematic review
DeLuzio MR, Moores C, Dhamija A, Wang Z, Cha C, Boffa DJ, Detterbeck FC, Kim AW. Resection of oligometastatic lung cancer to the pancreas may yield a survival benefit in select patients – A systematic review. Pancreatology 2015, 15: 456-462. PMID: 25900320, DOI: 10.1016/j.pan.2015.03.014.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerOligometastatic lung cancerCurative-intent resectionLung cancerSystematic reviewMedian survivalSurvival benefitPancreatic metastasisPrimary lung malignancyOverall median survivalSignificant survival benefitCox regression analysisCell lung cancerMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsSurveillance CTPalliative surgeryMetachronous presentationPancreatic headSelect patientsSurgical therapyLung malignancyKaplan-MeierPatientsReporting Items
2007
Beliefs among Physicians in the Diagnostic and Therapeutic Approach to Non-small Cell Lung Cancer
Stinchcombe TE, Detterbeck FC, Lin L, Rivera MP, Socinski MA. Beliefs among Physicians in the Diagnostic and Therapeutic Approach to Non-small Cell Lung Cancer. Journal Of Thoracic Oncology 2007, 2: 819-826. PMID: 17805059, DOI: 10.1097/jto.0b013e31811f478a.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Non-Small-Cell LungClinical CompetenceCombined Modality TherapyFemaleHumansLung NeoplasmsMaleNeoplasm StagingOutcome Assessment, Health CarePractice Guidelines as TopicQuality of LifeRetrospective StudiesSeverity of Illness IndexSurveys and QuestionnairesSurvival RateUnited StatesConceptsEvidence-based guidelinesStage IV diseaseSolitary pulmonary nodulesLung cancerPhysicians' beliefsPractice beliefsPulmonary nodulesNon-small cell lung cancerRole of chemotherapyStage III diseaseMediastinal lymph nodesPostoperative radiation therapyCell lung cancerTreatment of patientsMajority of physiciansQuality of lifePositron emission tomographyReminder e-mailsAdjuvant chemotherapyOperable patientsSurvival benefitChest PhysiciansLymph nodesPractice patternsRadiation therapy
2004
Systematic Review Evaluating the Timing of Thoracic Radiation Therapy in Combined Modality Therapy for Limited-Stage Small-Cell Lung Cancer
Fried DB, Morris DE, Poole C, Rosenman JG, Halle JS, Detterbeck FC, Hensing TA, Socinski MA. Systematic Review Evaluating the Timing of Thoracic Radiation Therapy in Combined Modality Therapy for Limited-Stage Small-Cell Lung Cancer. Journal Of Clinical Oncology 2004, 22: 4837-4845. PMID: 15570087, DOI: 10.1200/jco.2004.01.178.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Non-Small-Cell LungChemotherapy, AdjuvantCombined Modality TherapyConfidence IntervalsDose Fractionation, RadiationDose-Response Relationship, RadiationHumansLung NeoplasmsNeoplasm StagingOdds RatioPneumonectomyPrognosisRadiotherapy DosageRadiotherapy, AdjuvantRandomized Controlled Trials as TopicRisk AssessmentSurvival AnalysisTreatment OutcomeConceptsThoracic radiation therapyPlatinum-based chemotherapyRisk ratioRadiation therapyLS-SCLCLung cancerLimited-stage small cell lung cancerSmall cell lung cancerHyperfractionated radiation therapyLimited-Stage SmallProphylactic cranial irradiationCombined modality therapyCell lung cancerCranial irradiationChemotherapy regimensChemotherapeutic regimenModality therapySurvival benefitRandomized trialsDaily fractionationSubset analysisRadiation fractionationRT relativeRisk differenceChemotherapy