2010
Infectivity of Borrelia burgdorferi sensu lato is unaltered in C3-deficient mice
van Burgel ND, Balmus NC, Fikrig E, van Dam AP. Infectivity of Borrelia burgdorferi sensu lato is unaltered in C3-deficient mice. Ticks And Tick-borne Diseases 2010, 2: 20-26. PMID: 21771533, DOI: 10.1016/j.ttbdis.2010.10.003.Peer-Reviewed Original ResearchConceptsWT miceAbsence of C3B. burgdorferiB. afzeliiQuantitative PCRDifferent Borrelia speciesC3 knockout miceC3-deficient miceComplement-deficient miceWild-type miceB. afzelii infectionBorrelia burgdorferi sensu latoHuman complementInflammation scoreBurgdorferi sensu latoB. bavariensisAfzelii infectionBorrelia speciesKnockout miceMiceHeart tissueWeeksB. gariniiBurgdorferiSignificant differences
1998
Human granulocytic ehrlichiosis, a tick-borne disease.
Ijdo JW, Fikrig E. Human granulocytic ehrlichiosis, a tick-borne disease. Nederlands Tijdschrift Voor Geneeskunde 1998, 142: 1778-81. PMID: 9856144.Peer-Reviewed Original ResearchConceptsPresence of leukopeniaRecent tick biteDay of admissionWhite cell countPeripheral blood smearHuman granulocytic ehrlichiosisElevated transaminasesTick-borne diseaseSevere headachePlatelet countTick biteNormal limitsCell countBlood smearsGranulocytic ehrlichiosisDays durationFull recoveryMyalgiaEhrlichiosisHeadacheWeeksLaboratory resultsLaboratory testsDurationCount
1997
The Early Humoral Response in Human Granulocytic Ehrlichiosis
IJdo J, Zhang Y, Hodzic E, Magnarelli L, Wilson M, Telford S, Barthold S, Fikrig E. The Early Humoral Response in Human Granulocytic Ehrlichiosis. The Journal Of Infectious Diseases 1997, 176: 687-692. PMID: 9291316, DOI: 10.1086/514091.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisAntibody responseGranulocytic ehrlichiosisHGE agentC3H/HeJ miceEarly humoral responseEarly antibody responseStrong antibody responseHumoral responseHeJ miceClinical infectionPatientsAntigenHL-60 cellsMiceInfectionIgGEhrlichiosisSerumWeeksResponseIgMAgentsDiseaseDiagnosis