Adjuvant Chemotherapy in Older and Younger Women With Lymph Node–Positive Breast Cancer
Muss HB, Woolf S, Berry D, Cirrincione C, Weiss RB, Budman D, Wood WC, Henderson IC, Hudis C, Winer E, Cohen H, Wheeler J, Norton L, B F. Adjuvant Chemotherapy in Older and Younger Women With Lymph Node–Positive Breast Cancer. JAMA 2005, 293: 1073-1081. PMID: 15741529, DOI: 10.1001/jama.293.9.1073.Peer-Reviewed Original ResearchConceptsLymph node-positive breast cancerNode-positive breast cancerTreatment-related mortalityDisease-free survivalAdjuvant chemotherapyBreast cancerOverall survivalOlder womenMore chemotherapyOlder patientsHigh treatment-related mortalityAge groupsYoung womenPositive lymph nodesHealthy older patientsDuration of chemotherapyGood general healthSmaller tumor sizeBreast cancer mortalityBreast cancer patientsCommunity medical centerDifferent age groupsTamoxifen useLymph nodesRetrospective review