2018
CDK4/6 inhibition in breast cancer: current practice and future directions
Pernas S, Tolaney SM, Winer EP, Goel S. CDK4/6 inhibition in breast cancer: current practice and future directions. Therapeutic Advances In Medical Oncology 2018, 10: 1758835918786451. PMID: 30038670, PMCID: PMC6050811, DOI: 10.1177/1758835918786451.Peer-Reviewed Original ResearchCDK4/6 inhibitorsBreast cancerNovel immune-based therapiesPositive breast cancer patientsER-positive breast cancerProgression-free survivalImmune-based therapiesBreast cancer patientsCancer cell cycle arrestClinical trial resultsSelective CDK4/6 inhibitorsNormal breast epitheliumCyclin-dependent kinase 4Breast cancer cellsCyclin D/cyclin-dependent kinase 4Cancer cell cycleEndocrine therapyCDK4/6 pathwayCDK4/6 inhibitionCancer patientsCell cycle arrestClinical dataEstrogen receptorPreclinical studiesBreast epithelium
2005
Offering participants results of a clinical trial: sharing results of a negative study
Partridge AH, Wong JS, Knudsen K, Gelman R, Sampson E, Gadd M, Bishop KL, Harris JR, Winer EP. Offering participants results of a clinical trial: sharing results of a negative study. The Lancet 2005, 365: 963-964. PMID: 15766998, DOI: 10.1016/s0140-6736(05)71085-0.Peer-Reviewed Original ResearchConceptsClinical trialsNegative studiesPhase II trialClinical trial resultsClinical trial participantsII trialLocal recurrenceDuctal carcinomaBreast excisionTrial participantsResults of trialsTrial resultsTrialsMost participantsHigh ratePreliminary findingsWomenParticipantsPatientsCarcinomaRecurrenceExcisionEarly high rate
2004
Oncology Physician and Nurse Practices and Attitudes Regarding Offering Clinical Trial Results To Study Participants
Partridge AH, Hackett N, Blood E, Gelman R, Joffe S, Bauer-Wu S, Knudsen K, Emmons K, Collyar D, Schilsky RL, Winer EP. Oncology Physician and Nurse Practices and Attitudes Regarding Offering Clinical Trial Results To Study Participants. Journal Of The National Cancer Institute 2004, 96: 629-632. PMID: 15100341, DOI: 10.1093/jnci/djh096.Peer-Reviewed Original ResearchConceptsTrial resultsMost patientsOncology physiciansClinical trialsClinical trial resultsOncology clinical trialsPatientsEligible membersNurses' practicePatients' difficultiesRespondersNegative emotional effectsTrialsPhysiciansFuture studiesOne-fifthParticipantsStudy resultsCancerCliniciansNursesResults of studiesEmotional effects