2010
Cardiac Toxicity From Systemic Cancer Therapy: A Comprehensive Review
Curigliano G, Mayer EL, Burstein HJ, Winer EP, Goldhirsch A. Cardiac Toxicity From Systemic Cancer Therapy: A Comprehensive Review. Progress In Cardiovascular Diseases 2010, 53: 94-104. PMID: 20728696, DOI: 10.1016/j.pcad.2010.05.006.Peer-Reviewed Original ResearchConceptsCardiac adverse effectsCardiac toxicityCardiovascular toxicityNew drug developmentLeft ventricular ejection fraction declineVentricular ejection fraction declineAdverse effectsClassic chemotherapy agentsEjection fraction declinePotential cardiovascular toxicityRare serious complicationsNovel biologic agentsSignificant cardiac dysfunctionAcute coronary syndromeCongestive heart failureLong-term complicationsTypes of malignanciesSystemic cancer therapyLife-threatening eventsCancer therapyTyrosine kinase inhibitorsDrug developmentCardiovascular safetyCoronary syndromeBiologic agentsLetters: Andrew Seidman, Clifford Hudis, and Eric Winer on the Point-Counterpoint on Dosing for Paclitaxel for Ovarian Cancer (11/25/09 issue); Letters: Simone's OncOpinion: 'Professional Professional Careers for ‘Old’ Guys (12/10/09 issue), by Leonard Zwelling MD; Letters: “Advances in Bone Biology Research Setting Stage for New Cancer Therapies” (11/25/09 issue), by W. Reid Pitts, Jr., MD
Seidman A, Hudis C, Winer E, Zwelling L. Letters: Andrew Seidman, Clifford Hudis, and Eric Winer on the Point-Counterpoint on Dosing for Paclitaxel for Ovarian Cancer (11/25/09 issue); Letters: Simone's OncOpinion: 'Professional Professional Careers for ‘Old’ Guys (12/10/09 issue), by Leonard Zwelling MD; Letters: “Advances in Bone Biology Research Setting Stage for New Cancer Therapies” (11/25/09 issue), by W. Reid Pitts, Jr., MD. Oncology Times 2010, 32: 3-4. DOI: 10.1097/01.cot.0000368015.24121.d3.Peer-Reviewed Original Research
2009
Racial Differences in Definitive Breast Cancer Therapy in Older Women
Keating NL, Kouri E, He Y, Weeks JC, Winer EP. Racial Differences in Definitive Breast Cancer Therapy in Older Women. Medical Care 2009, 47: 765-773. PMID: 19536008, DOI: 10.1097/mlr.0b013e31819e1fe7.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedBlack or African AmericanBreast NeoplasmsChi-Square DistributionFemaleHealth Services ResearchHealthcare DisparitiesHospitalsHumansLogistic ModelsMastectomyMedicareMultivariate AnalysisPractice Patterns, Physicians'Quality of Health CareSEER ProgramSensitivity and SpecificitySocioeconomic FactorsUnited StatesWhite PeopleConceptsHigh-volume hospitalsDefinitive primary therapyHigh-quality hospitalsBreast-conserving surgeryBreast cancer therapyBreast cancerPrimary therapyWhite womenRacial disparitiesStage I/II breast cancerBlack womenPrimary breast cancer therapyEarly-stage breast cancerLow-volume hospitalsBreast cancer patientsBreast cancer surgeryPatterns of careSEER-Medicare databaseCancer therapyPopulation-based sampleOlder Black womenDefinitive therapyVolume hospitalsCancer surgeryCancer patients
2008
Self-Reported Practices and Attitudes of US Oncologists Regarding Off-Protocol Therapy
Peppercorn J, Burstein H, Miller FG, Winer E, Joffe S. Self-Reported Practices and Attitudes of US Oncologists Regarding Off-Protocol Therapy. Journal Of Clinical Oncology 2008, 26: 5994-6000. PMID: 19029413, DOI: 10.1200/jco.2008.18.1420.Peer-Reviewed Original ResearchConceptsUS oncologistsInvestigational cancer therapiesUS medical oncologistsSelf-reported practicesAdjuvant trastuzumabCommunity oncologistsMedical oncologistsOpen trialAcademic oncologistsClinical trialsTrial recruitmentOncologistsClinical issuesDevelopment of guidelinesInformed consentLack of consensusAnonymous surveyCancer therapyTrialsPatientsTherapyDemographic factorsRandom sampleMonthsFurther definition
2006
Use of experimental therapy outside of clinical trials among U.S. oncologists
Peppercorn J, Joffe S, Burstein H, Winer E. Use of experimental therapy outside of clinical trials among U.S. oncologists. Journal Of Clinical Oncology 2006, 24: 6047-6047. DOI: 10.1200/jco.2006.24.18_suppl.6047.Peer-Reviewed Original ResearchClinical trialsPractice settingsInvestigational cancer therapiesAttitudes of physiciansDemographic factorsU.S. oncologistsCommunity oncologistsMedical oncologistsTrial enrollmentAcademic oncologistsRecent trialsExperimental therapiesPatient's requestAmerican oncologistsOncology communityGuideline developmentOncologistsPatientsSignificant financial relationshipTrialsMonthsCancer therapyTherapyRandom sampleCare