2017
Increasing dietary EPA and DHA influence estimated fatty acid desaturase activity in systemic organs which is reflected in the red blood cell in mice
Davidson EA, Pickens CA, Fenton JI. Increasing dietary EPA and DHA influence estimated fatty acid desaturase activity in systemic organs which is reflected in the red blood cell in mice. International Journal Of Food Sciences And Nutrition 2017, 69: 183-191. PMID: 28697636, DOI: 10.1080/09637486.2017.1348494.Peer-Reviewed Original ResearchConceptsDietary eicosapentaenoic acidEnzyme activity estimatesRed blood cellsDocosahexaenoic acidEicosapentaenoic acidDesaturase activityBlood cellsPhospholipid FA compositionDelta-6 desaturaseDHA influencesFatty acid metabolismTissue FA compositionFatty acid desaturase activitySystemic organsAdipose tissuePercent of energyFA compositionDelta 5Acid metabolismMuscleTissueMiceDifferential influenceCellsLung
2016
Red blood cell PUFAs reflect the phospholipid PUFA composition of major organs
Fenton JI, Gurzell EA, Davidson EA, Harris WS. Red blood cell PUFAs reflect the phospholipid PUFA composition of major organs. Prostaglandins Leukotrienes And Essential Fatty Acids 2016, 112: 12-23. PMID: 27637336, DOI: 10.1016/j.plefa.2016.06.004.Peer-Reviewed Original ResearchConceptsRed blood cellsCoronary heart diseasePhospholipid fatty acid compositionNumerous clinical trialsAmerican Heart AssociationPotential risk factorsFatty acid compositionFatty acidsFatty acid levelsLCPUFA exposureLCPUFA profilesRBC SFADietary SFAHeart AssociationLCPUFA levelsHeart diseaseRisk factorsClinical trialsCurrent recommendationsDietary supplementationMouse dietHealth outcomesNutritional supplementsMajor organsLCPUFA