2024
The Role of Sex and Gender Differences in Psychosocial Treatment Strategies for Autism Spectrum Disorder
Zhong J, Ahmad E, Kalvin C, Sukhodolsky D. The Role of Sex and Gender Differences in Psychosocial Treatment Strategies for Autism Spectrum Disorder. 2024, 129-155. DOI: 10.1007/978-3-031-62072-0_9.Peer-Reviewed Original ResearchAutism spectrum disorderSex differencesSpectrum disorderPsychosocial treatment strategiesAccumulating body of researchAutism spectrumBody of researchAutismGender differencesExperiences of individualsDisordersTreatment deliveryAccumulating bodyInterventionSexIndividualsTreatment strategiesDifferencesLevel of effectivenessSymptomsResearchGender89. Shared Disruptions in Neural Circuits of Eye Gaze Processing in Autism Spectrum Disorder and Schizophrenia
Ibrahim K, Iturmendi-Sabater I, Vasishth M, Barron D, Guardavaccaro M, Holmes A, McCarthy G, Eickhoff S, Sukhodolsky D. 89. Shared Disruptions in Neural Circuits of Eye Gaze Processing in Autism Spectrum Disorder and Schizophrenia. Biological Psychiatry 2024, 95: s135-s136. DOI: 10.1016/j.biopsych.2024.02.324.Peer-Reviewed Original ResearchAutism Spectrum Disorder (ASD)
Rutten M, Zhong J, Rolison M, Sukhodolsky D. Autism Spectrum Disorder (ASD). 2024 DOI: 10.1016/b978-0-323-95702-1.00076-2.ChaptersAutism spectrum disorderSeverity of core symptomsIdentity-first languagePerson-first languageCore symptomsPsychiatric disordersRestricted interestsIntellectual disabilityRepetitive behaviorsSpectrum disorderSensory sensitivityNeurodevelopmental disordersSocial communicationAutismEnvironmental risk factorsAutism communityPharmacological interventionsDisordersAdvanced parental ageParental ageADHDAnxietyLanguagePhenotypic presentationDisability
2023
Aggression Is Associated With Social Adaptive Functioning in Children With ASD and Anxiety
Kalvin C, Jordan R, Rowley S, Weis A, Ibrahim K, Sukhodolsky D. Aggression Is Associated With Social Adaptive Functioning in Children With ASD and Anxiety. Focus On Autism And Other Developmental Disabilities 2023, 38: 168-176. PMID: 38469453, PMCID: PMC10927274, DOI: 10.1177/10883576231165265.Peer-Reviewed Original ResearchAutism spectrum disorderSocial adaptive skillsAdaptive skillsSocial adaptiveAggressive behaviorSocial adaptive functioningSample of childrenAdaptive functioningASD diagnosisSpectrum disorderSocial functioningAge 8SkillsChildrenFunctioningAggressionAnxietyBehaviorParticipantsDisordersFindingsAdaptive
2022
Social and Adaptive Functioning in Tourette Syndrome
Sukhodolsky D, Kalvin C, Artukoğlu B, Eicher V, Leckman J. Social and Adaptive Functioning in Tourette Syndrome. 2022, 391-404. DOI: 10.1093/med/9780197543214.003.0023.Peer-Reviewed Original ResearchAdaptive functioningAttention-deficit/hyperactivity disorderTourette syndromeThorough clinical assessmentCo-occurring disordersHyperactivity disorderQuality of lifePsychosocial interventionsClinical assessmentBehavioral disordersSymptom severityFunctioningStandardized ratingsDisordersActive investigationImpairmentSyndromeSeverity
2021
Conducting CBT for Anxiety in Children with Autism Spectrum Disorder During COVID-19 Pandemic
Kalvin CB, Jordan RP, Rowley SN, Weis A, Wood KS, Wood JJ, Ibrahim K, Sukhodolsky DG. Conducting CBT for Anxiety in Children with Autism Spectrum Disorder During COVID-19 Pandemic. Journal Of Autism And Developmental Disorders 2021, 51: 4239-4247. PMID: 33385281, PMCID: PMC7775616, DOI: 10.1007/s10803-020-04845-1.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyAutism spectrum disorderSpectrum disorderEngagement of childrenChild anxietyExposure exercisesTreatment fidelityCOVID-19 pandemicAnxietyTelehealth deliveryTreatment targetsChildrenRemote deliveryDisordersTreatment deliveryResearch protocolParentsQuarantine restrictionsEngagementPandemicNew reality
2020
Assessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index
Kalvin CB, Gladstone TR, Jordan R, Rowley S, Marsh CL, Ibrahim K, Sukhodolsky DG. Assessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index. Journal Of Autism And Developmental Disorders 2020, 51: 1496-1507. PMID: 32734421, PMCID: PMC7855357, DOI: 10.1007/s10803-020-04627-9.Peer-Reviewed Original Research
2019
Anger Rumination is Associated with Restricted and Repetitive Behaviors in Children with Autism Spectrum Disorder
Ibrahim K, Kalvin C, Marsh CL, Anzano A, Gorynova L, Cimino K, Sukhodolsky DG. Anger Rumination is Associated with Restricted and Repetitive Behaviors in Children with Autism Spectrum Disorder. Journal Of Autism And Developmental Disorders 2019, 49: 3656-3668. PMID: 31144231, PMCID: PMC7035789, DOI: 10.1007/s10803-019-04085-y.Peer-Reviewed Original Research
2018
Cognitive Behavioral Therapy for Anger and Aggression in a Child With Tourette’s Syndrome
Tudor M, Bertschinger E, Piasecka J, Sukhodolsky D. Cognitive Behavioral Therapy for Anger and Aggression in a Child With Tourette’s Syndrome. Clinical Case Studies 2018, 17: 220-232. DOI: 10.1177/1534650118782438.ChaptersTourette syndromeOppositional defiant disorderAnger outburstsPrimary clinical concernContext of TSBehavioral therapy treatmentCognitive behavioral therapy treatmentCognitive behavioral therapySelect supplementsUseful treatmentMotor ticsDisruptive behaviorClinical concernPosttreatment assessmentBehavioral therapyWeekly sessionsAnxiety disordersTherapy treatmentSyndromeNeurodevelopmental disordersSignificant decreaseDefiant disorderInitial assessmentDisordersAggressive behaviorAn Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder
Lewis AS, van Schalkwyk GI, Lopez MO, Volkmar FR, Picciotto MR, Sukhodolsky DG. An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder. Journal Of Autism And Developmental Disorders 2018, 48: 2748-2757. PMID: 29536216, PMCID: PMC6394231, DOI: 10.1007/s10803-018-3536-7.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderTransdermal nicotineDouble-blind crossover trialAggressive behaviorPreliminary efficacyAggressive symptomsSleep ratingsAggressionSubscale changesNicotinic acetylcholine receptorsNAChR agonistsPrimary outcomeNicotine treatmentCrossover trialExploratory trialΑ7 nAChRsAcetylcholine receptorsNicotineAdultsDisordersPlaceboNAChRsFurther investigationTrials
2014
Clinical Correlates and Predictors of Caregiver Strain in Children With Chronic Tic Disorders
Ramanujam K, Himle MB, Hayes LP, Woods DW, Scahill L, Sukhodolsky DG, Wilhelm S, Deckersbach T, Peterson AL, Specht M, Walkup JT, Chang S, Piacentini J. Clinical Correlates and Predictors of Caregiver Strain in Children With Chronic Tic Disorders. Children's Health Care 2014, 44: 249-263. PMID: 26855465, PMCID: PMC4739807, DOI: 10.1080/02739615.2014.948166.Peer-Reviewed Original ResearchChronic tic disorderCaregiver strainClinical correlatesInattention/hyperactivityTic disordersRandomized-controlled trialTic intensityParents of childrenCare providersBehavior therapyComorbid internalizingExternalizing problemsDisruptive behaviorChildrenObjective strainHyperactivityPredictorsDisordersCurrent studyBest predictorCorrelatesTherapyImpairmentTrialsExamination of Aggression and Self-injury in Children with Autism Spectrum Disorders and Serious Behavioral Problems
Carroll D, Hallett V, McDougle CJ, Aman MG, McCracken JT, Tierney E, Arnold LE, Sukhodolsky DG, Lecavalier L, Handen BL, Swiezy N, Johnson C, Bearss K, Vitiello B, Scahill L. Examination of Aggression and Self-injury in Children with Autism Spectrum Disorders and Serious Behavioral Problems. Child And Adolescent Psychiatric Clinics Of North America 2014, 23: 57-72. PMID: 24231167, PMCID: PMC4212264, DOI: 10.1016/j.chc.2013.08.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAggressionAnalysis of VarianceAntipsychotic AgentsChildChild Development Disorders, PervasiveChild, PreschoolChi-Square DistributionDouble-Blind MethodFemaleHumansIntelligence TestsMaleOutcome Assessment, Health CarePsychiatric Status Rating ScalesRandomized Controlled Trials as TopicRisperidoneSelf-Injurious BehaviorSeverity of Illness IndexConceptsAutism spectrum disorderSubtypes of aggressionSelf-injurious behaviorSpectrum disorderUnderstanding of aggressionSerious behavioral problemsParent interviewsBehavioral problemsSelf-InjuryAggressionStudy findingsChildrenRisperidone trialsChildren 2DisordersIndividualized treatmentPositive responseSubtypesFurther studiesBiological mechanismsHigh rateInterviewsFindingsNarrativesBehavior
2013
Social and Adaptive Functioning in Tourette Syndrome
Sukhodolsky D, Eicher V, Leckman J. Social and Adaptive Functioning in Tourette Syndrome. 2013, 468-484. DOI: 10.1093/med/9780199796267.003.0021.ChaptersExploring the Manifestations of Anxiety in Children with Autism Spectrum Disorders
Hallett V, Lecavalier L, Sukhodolsky DG, Cipriano N, Aman MG, McCracken JT, McDougle CJ, Tierney E, King BH, Hollander E, Sikich L, Bregman J, Anagnostou E, Donnelly C, Katsovich L, Dukes K, Vitiello B, Gadow K, Scahill L. Exploring the Manifestations of Anxiety in Children with Autism Spectrum Disorders. Journal Of Autism And Developmental Disorders 2013, 43: 2341-2352. PMID: 23400347, PMCID: PMC4038127, DOI: 10.1007/s10803-013-1775-1.Peer-Reviewed Original ResearchConceptsLow-functioning childrenAutism spectrum disorderUnderstanding of anxietyManifestations of anxietySocial anxietyBehavioral measuresSeparation anxietySpectrum disorderAnxiety symptomsHigh anxietyGeneralized anxietyAnxiety ScaleSleep difficultiesVerbal expressionAnxietyHigher scoresIQDSM-IVChildrenItemsASDWorryLanguageASDsDisorders
2008
Trial Design Challenges When Combining Medication and Parent Training in Children with Pervasive Developmental Disorders
Scahill L, Aman MG, McDougle CJ, Arnold LE, McCracken JT, Handen B, Johnson C, Dziura J, Butter E, Sukhodolsky D, Swiezy N, Mulick J, Stigler K, Bearss K, Ritz L, Wagner A, Vitiello B. Trial Design Challenges When Combining Medication and Parent Training in Children with Pervasive Developmental Disorders. Journal Of Autism And Developmental Disorders 2008, 39: 720-729. PMID: 19096921, PMCID: PMC4807607, DOI: 10.1007/s10803-008-0675-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAggressionBehavior TherapyChildChild Development Disorders, PervasiveCombined Modality TherapyDopamine AntagonistsFemaleHumansMaleOutpatientsParent-Child RelationsParentsPatient CompliancePersonality AssessmentPsychiatric Status Rating ScalesRisperidoneSelf-Injurious BehaviorTreatment OutcomeConceptsParent trainingAdaptive functioningPervasive developmental disorderMeasures of noncomplianceBehavioral interventionsSymptom reductionDevelopmental disordersTraining targetClinical treatment targetsTrial design challengesTreatment targetsFunctioningTrainingFunctional improvementLow doseTreatment groupsMedicationsClinical practiceTantrumsAggressionBeneficial effectsIrritabilityChildrenNoncomplianceDisorders
2007
The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder
Sukhodolsky DG, Leckman JF, Rothenberger A, Scahill L. The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder. European Child & Adolescent Psychiatry 2007, 16: 51-59. PMID: 17665283, DOI: 10.1007/s00787-007-1007-3.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderTourette syndromeAbnormal neural oscillationsOscillatory activityHyperactivity disorderAbnormal oscillatory activityThalamo-cortical circuitsSymptoms of ADHDNeural oscillationsNeural oscillatory activityBasal gangliaFunctional abnormalitiesNormal brainThalamocortical regionsThalamocortical oscillationsCortical regionsTransient hyperpolarizationPrefrontal cortexNeural activityNeural communicationPathophysiologyMotor controlSyndromeBrainDisordersDrug and non-drug treatments of children with ADHD and tic disorders
Poncin Y, Sukhodolsky DG, McGuire J, Scahill L. Drug and non-drug treatments of children with ADHD and tic disorders. European Child & Adolescent Psychiatry 2007, 16: 78-88. PMID: 17665286, DOI: 10.1007/s00787-007-1010-8.ChaptersConceptsAttention deficit hyperactivity disorderTreatment of ADHDTreatment of ticsTic disordersTreatment of childrenStimulant medicationWorsening of ticsNon-pharmacological approachesNon-drug treatmentsChronic tic disorderMinority of childrenDeficit hyperactivity disorderMild ticsSignificant morbiditySchool-aged childrenNovel treatmentsMedicationsLiterature searchPreponderance of evidenceAdverse effectsHyperactivity disorderDisordersMore studiesTreatmentChildren
2006
Randomized Trial of Parent Management Training in Children With Tic Disorders and Disruptive Behavior
Scahill L, Sukhodolsky DG, Bearss K, Findley D, Hamrin V, Carroll DH, Rains AL. Randomized Trial of Parent Management Training in Children With Tic Disorders and Disruptive Behavior. Journal Of Child Neurology 2006, 21: 650-656. PMID: 16970865, DOI: 10.1177/08830738060210080201.Peer-Reviewed Original ResearchConceptsTic disordersParent management trainingUsual groupClinical Global ImpressionShort-term efficacyRating Scale scoresShort-term improvementDisruptive behaviorRandomized trialsStable medicationBehavior rating scale scoresGlobal ImpressionParent management training programsClinical trialsImprovement ScaleScale scoreStructured parent training programTraining programTreatment assignmentParent training programTraining groupDisruptive behavior problemsDisordersClinical samplesSevere levels
2005
Public health significance of tic disorders in children and adolescents.
Scahill L, Sukhodolsky DG, Williams SK, Leckman JF. Public health significance of tic disorders in children and adolescents. Advances In Neurology 2005, 96: 240-8. PMID: 16383223.Peer-Reviewed Original ResearchConceptsTic disordersPresence of ADHDAbsence of ADHDPublic health significanceCommunity sampleMild ticsPersistent ticsGreater disabilityVocal ticsDaily livingDisruptive behaviorChronic ticsHealth significanceDisordersClinical samplesCommunity surveyChildrenADHDMinimal consequencesMultiple motorsImpairment