Update of the human and mouse SERPINgene superfamily
Heit C, Jackson BC, McAndrews M, Wright MW, Thompson DC, Silverman GA, Nebert DW, Vasiliou V. Update of the human and mouse SERPINgene superfamily. Human Genomics 2013, 7: 22. PMID: 24172014, PMCID: PMC3880077, DOI: 10.1186/1479-7364-7-22.Peer-Reviewed Original ResearchConceptsHuman protein-coding genesMultiple paralogous genesProtein-coding genesParalogous genesSerine proteinase inhibitorFunctional genesSerpin geneIntracellular serpinsSerpin familyGenesProteinase inhibitorsSerpinsCancer metastasisFurther characterizationProteinTherapeutic targetChaperonesPseudogenesGenomeBlood clottingImmune functionPotential biomarkersInhibitorsTumorigenesisRole