Enzymatic Modulation of Vasoactive Intestinal Peptide and Nonadrenergic Noncholinergic Inhibitory Responses in Guinea Pig Tracheae
Thompson D, Diamond L, Altiere R. Enzymatic Modulation of Vasoactive Intestinal Peptide and Nonadrenergic Noncholinergic Inhibitory Responses in Guinea Pig Tracheae. American Journal Of Respiratory And Critical Care Medicine 1990, 142: 1119-1123. PMID: 2240834, DOI: 10.1164/ajrccm/142.5.1119.Peer-Reviewed Original ResearchConceptsVasoactive intestinal peptideNANC inhibitory responsesGuinea pig tracheaConcentration-response curvesInhibitory responsesIntestinal peptideInhibitory systemPig tracheaNonadrenergic noncholinergic inhibitory responsesVIP concentration-response curveExogenous vasoactive intestinal peptideRelaxation responseExogenous VIP administrationNANC inhibitory neurotransmitterNANC nerve stimulationNANC relaxation responsesNoncholinergic inhibitory responsesElectrical field stimulationSoybean trypsin inhibitorAdrenergic inhibitoryTachykinin depletionCholinergic excitatoryVIP administrationAutonomic nervesNerve stimulation