Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures
Saw YT, Yang J, Ng SK, Liu S, Singh S, Singh M, Welch WR, Tsuda H, Fong WP, Thompson D, Vasiliou V, Berkowitz RS, Ng SW. Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures. BMC Cancer 2012, 12: 329. PMID: 22852552, PMCID: PMC3458927, DOI: 10.1186/1471-2407-12-329.Peer-Reviewed Original ResearchConceptsClear cell tumorsWestern blot analysisCell tumorsOvarian tissueALDH isozymesCancer cellsClear cell subtypeSphere cultureOvarian cancer tissuesQuantitative reverse transcription polymerase chain reactionNormal ovarian tissuesOvarian epithelial tumorsReverse transcription-polymerase chain reactionHuman ovarian cancerOvarian tumor tissuesTranscription-polymerase chain reactionOvarian cancer cellsBlot analysisHuman cancer stem cellsCancer stem cellsOvarian cancer pathophysiologyMRNA expression levelsResultsImmunohistochemical stainingCancer cell linesMucinous tumors