2023
Phthalates and Incident Diabetes in Midlife Women: The Study of Women's Health Across the Nation (SWAN)
Peng M, Karvonen-Gutierrez C, Herman W, Mukherjee B, Park S. Phthalates and Incident Diabetes in Midlife Women: The Study of Women's Health Across the Nation (SWAN). The Journal Of Clinical Endocrinology & Metabolism 2023, 108: 1947-1957. PMID: 36752637, PMCID: PMC10348472, DOI: 10.1210/clinem/dgad033.Peer-Reviewed Original ResearchMeSH KeywordsDiabetes MellitusEnvironmental ExposureEnvironmental PollutantsFemaleHumansPhthalic AcidsWomen's HealthConceptsStudy of Women's HealthIncidence of diabetesWomen's HealthIncident diabetesMono-carboxyisononyl phthalatePhthalate metabolitesAssociated with diabetes incidenceHazard ratioCohort of midlife womenHealth-related factorsRacially/ethnically diverse cohortHigh-molecular-weight phthalate metabolitesTime-varying exposureCox proportional hazards modelsProportional hazards modelEffect modificationMono-isobutyl phthalateRacial/ethnic groupsDiabetes incidenceMono(3-carboxypropyl) phthalateMidlife womenMono-carboxyoctyl phthalateWhite womenAsian womenLongitudinal evidence
2022
Per- and polyfluoroalkyl substances and incident diabetes in midlife women: the Study of Women’s Health Across the Nation (SWAN)
Park S, Wang X, Ding N, Karvonen-Gutierrez C, Calafat A, Herman W, Mukherjee B, Harlow S. Per- and polyfluoroalkyl substances and incident diabetes in midlife women: the Study of Women’s Health Across the Nation (SWAN). Diabetologia 2022, 65: 1157-1168. PMID: 35399113, PMCID: PMC9177697, DOI: 10.1007/s00125-022-05695-5.Peer-Reviewed Original ResearchMeSH KeywordsDiabetes MellitusEnvironmental PollutantsFemaleFluorocarbonsGlucoseHumansProspective StudiesWomen's HealthConceptsStudy of Women's HealthIncident diabetesWomen's HealthPolyfluoroalkyl substancesDiabetes riskMidlife womenSelf-reported diabetesTotal energy intakeProspective cohort studyIncreased diabetes riskCox proportional hazards modelsPhysical activityGlucose-lowering medicationsProportional hazards modelResultsAfter adjustmentNation Multi-Pollutant StudyBottom tertileSmoking statusHighest tertileAlcohol consumptionDiabetes-free womenFollow-up visitG-computationQuantile-based g-computationCohort study
2020
Urinary metals and incident diabetes in midlife women: Study of Women’s Health Across the Nation (SWAN)
Wang X, Karvonen-Gutierrez C, Herman W, Mukherjee B, Harlow S, Park S. Urinary metals and incident diabetes in midlife women: Study of Women’s Health Across the Nation (SWAN). BMJ Open Diabetes Research & Care 2020, 8: e001233. PMID: 32747380, PMCID: PMC7398092, DOI: 10.1136/bmjdrc-2020-001233.Peer-Reviewed Original ResearchConceptsUrinary metal concentrationsMetal concentrationsMetal mixturesUrinary excretion of zincStudy of Women's HealthExposure to metal mixturesExcretion of zincIncident diabetesWomen's HealthAssociated with higher risk of diabetesSelf-reported doctor-diagnosed diabetesMidlife womenAssociated with higher riskUrinary metalsHigh risk of diabetesCox proportional hazards modelsIncreased urinary excretionMultiethnic Cohort StudyFree of diabetesHigher overall exposureIncreased urinary excretion of zincAssociated with elevated riskRisk of diabetesDoctor-diagnosed diabetesHigher urinary concentrations