2016
Repeated measures of inflammation and oxidative stress biomarkers in preeclamptic and normotensive pregnancies
Ferguson K, Meeker J, McElrath T, Mukherjee B, Cantonwine D. Repeated measures of inflammation and oxidative stress biomarkers in preeclamptic and normotensive pregnancies. American Journal Of Obstetrics And Gynecology 2016, 216: 527.e1-527.e9. PMID: 28043842, PMCID: PMC5420472, DOI: 10.1016/j.ajog.2016.12.174.Peer-Reviewed Original ResearchConceptsTumor necrosis factor-aNormotensive pregnanciesC-reactive proteinMeasures of inflammationHazard ratioOxidative stress biomarkersInterleukin-1bTime pointsInflammation biomarkersStudy visitsTime of preeclampsia diagnosisPrediction of preeclampsiaOxidative stressHigher body mass indexOxidative stress biomarker 8-isoprostaneStress biomarkersCox proportional hazards modelsCompared to other time pointsBody mass indexProspective birth cohortCalculate hazard ratiosSmall study populationPanel of inflammationFactor AProportional hazards model
2015
Associations between Maternal Biomarkers of Phthalate Exposure and Inflammation Using Repeated Measurements across Pregnancy
Ferguson K, McElrath T, Mukherjee B, Loch-Caruso R, Meeker J. Associations between Maternal Biomarkers of Phthalate Exposure and Inflammation Using Repeated Measurements across Pregnancy. PLOS ONE 2015, 10: e0135601. PMID: 26317519, PMCID: PMC4552851, DOI: 10.1371/journal.pone.0135601.Peer-Reviewed Original ResearchConceptsC-reactive proteinPregnant womenPhthalate exposureInvestigate inflammationInflammation biomarkersAnalysis of pregnant womenAssociated with adverse reproductive outcomesBiomarkers of phthalate exposureUrinary phthalate metabolitesAssociated with IL-6Plasma inflammation biomarkersMono-benzyl phthalateAdverse reproductive outcomesStatistically significant associationUrinary metabolite concentrationsMaternal biomarkersPeripheral inflammationPhthalate effectsPhthalate metabolitesIL-6Reproductive outcomesInflammationMono-benzylSignificant associationTarget tissues
2014
Urinary Phthalate Metabolite Associations with Biomarkers of Inflammation and Oxidative Stress Across Pregnancy in Puerto Rico
Ferguson K, Cantonwine D, Rivera-González L, Loch-Caruso R, Mukherjee B, Del Toro L, Jiménez-Vélez B, Calafat A, Ye X, Alshawabkeh A, Cordero J, Meeker J. Urinary Phthalate Metabolite Associations with Biomarkers of Inflammation and Oxidative Stress Across Pregnancy in Puerto Rico. Environmental Science And Technology 2014, 48: 7018-7025. PMID: 24845688, PMCID: PMC4066910, DOI: 10.1021/es502076j.Peer-Reviewed Original ResearchConceptsMono-n-butyl phthalateBiomarkers of inflammationIL-10Prospective cohort study of pregnant womenDi-2-ethylhexyl phthalate metabolitesCohort study of pregnant womenIL-6Study of pregnant womenAssociated with increased IL-6Oxidative stressUrinary phthalate metabolitesC-reactive proteinProspective cohort studyAdverse birth outcomesMetabolites of di-2-ethylhexyl phthalateOxidative stress markersPreterm birthMetabolite associationsPregnant womenMono-n-butylDi-2-ethylhexyl phthalateOxidative stress biomarkersBirth outcomesTNF-aInflammation biomarkers