2005
Negative Regulation of Monocyte Adhesion to Arterial Elastic Laminae by Signal Regulatory Protein α and Src Homology 2 Domain-containing Protein-Tyrosine Phosphatase-1*
Liu SQ, Alkema PK, Tieché C, Tefft BJ, Liu DZ, Li YC, Sumpio BE, Caprini JA, Paniagua M. Negative Regulation of Monocyte Adhesion to Arterial Elastic Laminae by Signal Regulatory Protein α and Src Homology 2 Domain-containing Protein-Tyrosine Phosphatase-1*. Journal Of Biological Chemistry 2005, 280: 39294-39301. PMID: 16159885, DOI: 10.1074/jbc.m503866200.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArteriesCell AdhesionElastic TissueIn Vitro TechniquesIntracellular Signaling Peptides and ProteinsLeukocytesMonocytesPhosphorylationProtein Phosphatase 1Protein Tyrosine Phosphatase, Non-Receptor Type 6Protein Tyrosine PhosphatasesRatsRats, Sprague-DawleyReceptors, Cell SurfaceRNA, Small InterferingConceptsSHP-1Arterial elastic laminaeSrc homology 2 domain-containing protein tyrosine phosphataseSIRP-alphaSrc homology 2 domain-containing protein tyrosine phosphatase 1Protein tyrosine phosphatase 1Protein tyrosine phosphataseSignal regulatory protein alphaSignal regulatory protein αRegulatory protein alphaExtracellular matrix constituentsMonocyte adhesionArterial morphogenesisPhosphatase 1Regulatory protein αNegative regulationProtein alphaProtein αImportant functionsInduced activationDegradation peptidesInhibitory effectElasticity of arteriesAdhesionMatrix constituents
1995
Endothelins: polyfunctional cytokines.
McMillen MA, Sumpio BE. Endothelins: polyfunctional cytokines. Journal Of The American College Of Surgeons 1995, 180: 621-37. PMID: 7749544.Peer-Reviewed Original ResearchAdrenal GlandsAmino Acid SequenceCell Transformation, NeoplasticCytokinesDigestive SystemEndothelinsEndothelium, VascularHumansInsulinKidneyLiverLungMacrophagesMolecular Sequence DataMonocytesMuscle, Smooth, VascularMyocardiumNeutrophilsParathyroid GlandsPeripheral Vascular DiseasesPituitary Gland, AnteriorProtein BindingReceptors, EndothelinThyroid GlandEndothelial-leukocyte interactions in the neutrophil cascade
McMillen M, Sumpio B. Endothelial-leukocyte interactions in the neutrophil cascade. The American Journal Of Surgery 1995, 169: 186-187. PMID: 7817990, DOI: 10.1016/s0002-9610(99)80130-5.Peer-Reviewed Original ResearchEndothelin-1 increases intracellular calcium in human monocytes and causes production of interleukin-6
McMillen M, Huribal M, Cunningham M, Kumar R, Sumpio B. Endothelin-1 increases intracellular calcium in human monocytes and causes production of interleukin-6. Critical Care Medicine 1995, 23: 34-40.. PMID: 8001384, DOI: 10.1097/00003246-199501000-00009.Peer-Reviewed Original ResearchConceptsEndothelin-1Intracellular calciumHuman monocytesIL-6Production of interleukinIL-6 productionIL-1 productionIntracellular calcium concentrationBasic science laboratoryM endothelinInterleukin-6Healthy donorsFura-2Control monocytesIschemic endotheliumMonocytesEndothelinCalcium concentrationMean valueCalciumTissue cultureInterleukinPhytohemagglutininEndotheliumEndotoxin
1994
ENDOTHELIN-STIMULATED MONOCYTE SUPERNATANTS ENHANCE NEUTROPHIL SUPEROXIDE PRODUCTION
Huribal M, Kumar R, Cunningham M, Sumpio B, McMillen M. ENDOTHELIN-STIMULATED MONOCYTE SUPERNATANTS ENHANCE NEUTROPHIL SUPEROXIDE PRODUCTION. Shock 1994, 1: 184-187. PMID: 7735949, DOI: 10.1097/00024382-199403000-00005.Peer-Reviewed Original ResearchConceptsEndothelin-1Neutrophil superoxide productionIL-8Monocyte supernatantsSuperoxide productionInterleukin-8 contentHuman peripheral blood monocytesPotent neutrophil activatorVascular smooth musclePeripheral blood monocytesIncubation of neutrophilsInterleukin-6M ETNeutrophil activatorProstaglandin E2Smooth muscleVasoconstrictive peptideBlood monocytesMonocytesBasal levelsNeutrophilsSupernatantH incubationDirect effectEndothelin
1993
Endothelin-Stimulated Human Monocytes Produce Prostaglandin E2 but Not Leukotriene B4
McMillen M, Huribal M, Kumar R, Sumpio B. Endothelin-Stimulated Human Monocytes Produce Prostaglandin E2 but Not Leukotriene B4. Journal Of Surgical Research 1993, 54: 331-335. PMID: 8392650, DOI: 10.1006/jsre.1993.1053.Peer-Reviewed Original ResearchConceptsProstaglandin E2Pg/Human monocytesPost-traumatic immunosuppressionMonocytes/macrophagesBacterial lipopolysaccharide (LPS) stimulationEndothelin increaseM endothelinInterleukin-6Immune functionLeukotriene B4PGE2 productionVascular endotheliumEndothelinLipopolysaccharide (LPS) stimulationInjuryMonocytesAcid peptideE2B4HrActivationImmunosuppressionIschemiaMajor role