2012
169
Oda S, Hirasawa H, Sumpio B. 169. Critical Care Medicine 2012, 40: 1-328. DOI: 10.1097/01.ccm.0000424389.66537.91.Peer-Reviewed Original ResearchTF RNA expressionHigh TF expressionTF expressionTissue factorEndothelial cellsChemical stimulationRNA expressionExcessive inflammatory reactionReal-time RT-PCRLaminar flowVascular endothelial cellsQuantitative real-time RT-PCRHemodynamic stabilizationIntravascular activationIntravascular thrombosisFro flowInflammatory reactionExtrinsic coagulationTumor growth
2011
Varying Effects of Hemodynamic Forces on Tissue Factor RNA Expression in Human Endothelial Cells
Abe R, Yamashita N, Rochier A, Nixon A, Abe R, Madri JA, Sumpio BE. Varying Effects of Hemodynamic Forces on Tissue Factor RNA Expression in Human Endothelial Cells. Journal Of Surgical Research 2011, 170: 150-156. PMID: 21592524, DOI: 10.1016/j.jss.2011.04.002.Peer-Reviewed Original ResearchConceptsLaminar flowOscillatory flowCyclic strainUnidirectional laminar flowUniform laminar flowMechanical stressDisturbed flowTF RNA expressionHuman umbilical vein endothelial cellsFlowStatic controlHigh TF expressionTF expressionForceMechanical forcesEndothelial cellsRNA expressionSustained amplificationPulsatile to-fro flow induces greater and sustained expression of tissue factor RNA in HUVEC than unidirectional laminar flow
Abe R, Yamashita N, Rochier A, Abe R, Nixon A, Madri JA, Sumpio BE. Pulsatile to-fro flow induces greater and sustained expression of tissue factor RNA in HUVEC than unidirectional laminar flow. AJP Heart And Circulatory Physiology 2011, 300: h1345-h1351. PMID: 21257914, PMCID: PMC3075035, DOI: 10.1152/ajpheart.01197.2010.Peer-Reviewed Original Research