2024
Intravenous Thrombolysis in Patients With Cervical Artery Dissection: A Secondary Analysis of the STOP-CAD Study.
Shu L, Akpokiere F, Mandel D, Field T, Leon Guerrero C, Henninger N, Muppa J, Affan M, Haq Lodhi O, Heldner M, Antonenko K, Seiffge D, Arnold M, Salehi Omran S, Crandall R, Lester E, López-Mena D, Arauz A, Nehme A, Boulanger M, Touzé E, Sousa J, Sargento-Freitas J, Barata V, Castro-Chaves P, Brito M, Khan M, Mallick D, Rothstein A, Khazaal O, Kaufmann J, Engelter S, Traenka C, Aguiar de Sousa D, Soares M, Rosa S, Zhou L, Gandhi P, Mancini S, Metanis I, Leker R, Pan K, Dantu V, Baumgartner K, Burton T, Von Rennenberg R, Nolte C, Choi R, MacDonald J, Bavarsad Shahripour R, Guo X, Ghannam M, Almajali M, Samaniego E, Rioux B, Zine-Eddine F, Poppe A, Fonseca A, Baptista M, Cruz D, Romoli M, De Marco G, Longoni M, Keser Z, Griffin K, Kuohn L, Frontera J, Amar J, Giles J, Zedde M, Pascarella R, Grisendi I, Nzwalo H, Liebeskind D, Molaie A, Cavalier A, Kam W, Mac Grory B, Al Kasab S, Anadani M, Kicielinski K, Eltatawy A, Chervak L, Chulluncuy Rivas R, Aziz Y, Mistry E, Bakradze E, Tran T, Rodrigo-Gisbert M, Requena M, Saleh Velez F, Garcia J, Muddasani V, de Havenon A, Sanchez S, Vishnu V, Yaddanapudi S, Adams L, Browngoehl A, Ranasinghe T, Dunston R, Lynch Z, Penckofer M, Siegler J, Mayer S, Willey J, Zubair A, Cheng Y, Sharma R, Marto J, Krupka D, Klein P, Nguyen T, Asad S, Sarwat Z, Balabhadra A, Patel S, Secchi T, Martins S, Mantovani G, Kim Y, Krishnaiah B, Elangovan C, Lingam S, Qureshi A, Fridman S, Alvarado A, Khasiyev F, Linares G, Mannino M, Terruso V, Tountopoulou A, Tentolouris-Piperas V, Martinez-Marino M, Carrasco Wall V, Indraswari F, El Jamal S, Liu S, Zhou M, Alvi M, Ali F, Sarvath M, Morsi R, Kass-Hout T, Shi F, Zhang J, Sokhi D, Said J, Mongare N, Simpkins A, Gomez R, Sen S, Ghani M, Elnazeir M, Wangqin R, Xiao H, Kala N, Khan F, Stretz C, Mohammadzadeh N, Goldstein E, Furie K, Yaghi S. Intravenous Thrombolysis in Patients With Cervical Artery Dissection: A Secondary Analysis of the STOP-CAD Study. Neurology 2024, 103: e209843. PMID: 39298709, PMCID: PMC11415265, DOI: 10.1212/wnl.0000000000209843.Peer-Reviewed Original ResearchConceptsAcute ischemic stroke symptomsCervical artery dissectionFunctional independenceIntravenous thrombolysisIschemic stroke symptomsStroke symptomsArtery dissectionIncidence of symptomatic intracranial hemorrhageIschemic strokeSymptomatic intracranial hemorrhageSuspected ischemic strokeClass III evidenceMedian ageSymptomatic ICHIntracranial hemorrhageSecondary analysisGuideline recommendationsICH riskIII evidenceFunctional outcomesPatientsThrombolysisCeADYoung adultsDissectionPatients’ experiences with methylcobalamin injections in amyotrophic lateral sclerosis
Zubair A, Saab L, Scharer K, Khokhar B. Patients’ experiences with methylcobalamin injections in amyotrophic lateral sclerosis. Brain Circulation 2024, 10: 60-66. PMID: 38655443, PMCID: PMC11034440, DOI: 10.4103/bc.bc_17_23.Peer-Reviewed Original ResearchVitamin B12 injectionsB12 injectionsAmyotrophic lateral sclerosisFood and Drug Administration-approved treatmentPrescribed off-labelQuality of lifeProgressive motor neuron diseaseVitamin B12Pool of patientsMethylcobalamin injectionRandomized controlled trialsLateral sclerosisOff-labelMotor neuron diseaseDisease progressionPatientsMuscle functionSemi-structured interviewsImprove balance
2023
“Hot nose” sign in brain death
Zubair A. “Hot nose” sign in brain death. Surgical Neurology International 2023, 14: 282. PMID: 37680934, PMCID: PMC10481819, DOI: 10.25259/sni_543_2023.Peer-Reviewed Original ResearchBrain deathArterial activityBrain death testingBrain-dead patientsExternal carotid arteryMotor vehicle accidentsSubdural hematomaEmergency roomBrainstem responseCarotid arteryAncillary testingBrain scansVehicle accidentsSkull baseDeath testingMeticulous examinationNoseDeathExaminationSignsHematomaHemorrhagePatientsArteryThe Impact of COVID-19 on Families With Pediatric Muscular Dystrophy Patients
Zubair A, Scharer K, Lembeck P, Ionita C, Roy B. The Impact of COVID-19 on Families With Pediatric Muscular Dystrophy Patients. Cureus 2023, 15: e41138. PMID: 37519528, PMCID: PMC10386847, DOI: 10.7759/cureus.41138.Peer-Reviewed Original ResearchPediatric patientsCOVID-19 pandemicMuscular dystrophyCoronavirus disease 2019 (COVID-19) pandemicDisease 2019 pandemicParents/caregiversMuscular dystrophy patientsChart reviewCaregiver burdenHome ordersPerson visitsLong-term effectsNeuromuscular conditionsProvider careNeuromuscular disordersPatientsPsychosocial impactDystrophy patientsSchool closuresNeuromuscular disabilitiesMajority of familiesHealthcare servicesSocial distancing measuresCOVID-19Daily activitiesNeurologic Complications of Babesiosis, United States, 2011–2021 - Volume 29, Number 6—June 2023 - Emerging Infectious Diseases journal - CDC
Locke S, O’Bryan J, Zubair A, Rethana M, Moffarah A, Krause P, Farhadian S. Neurologic Complications of Babesiosis, United States, 2011–2021 - Volume 29, Number 6—June 2023 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2023, 29: 1127-1135. PMID: 37209667, PMCID: PMC10202888, DOI: 10.3201/eid2906.221890.Peer-Reviewed Original ResearchConceptsNeurologic complicationsNeurologic symptomsRisk factorsYale-New Haven HospitalInfectious Diseases journal - CDCHigh-grade parasitemiaNeurologic risk factorsRange of symptomsAdult patientsRenal failureDiabetes mellitusFrequent symptomsHospital admissionImpaired consciousnessMedical recordsEndemic areasParasitic infectionsPatientsSymptomsIntraerythrocytic protozoaComplicationsBabesiosisNew HavenDeliriumMellitusHemorrhagic Conversion of Acute Ischemic Stroke
Zubair A, Sheth K. Hemorrhagic Conversion of Acute Ischemic Stroke. Neurotherapeutics 2023, 20: 705-711. PMID: 37085684, PMCID: PMC10275827, DOI: 10.1007/s13311-023-01377-1.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeHemorrhagic conversionIschemic strokeTreatment of patientsHemorrhagic transformationEndovascular thrombectomySerious complicationsThrombolytic therapyTreatment optionsRisk factorsLeading causePatient outcomesCurrent treatmentTimely managementStrokePatientsTreatmentThrombectomyMorbidityComplicationsReviewPathophysiologyTherapyMortalityDiagnosis
2022
Predictors of Recurrent Venous Thrombosis After Cerebral Venous Thrombosis
Shu L, Bakradze E, Omran SS, Giles J, Amar J, Henninger N, Elnazeir M, Liberman A, Moncrieffe K, Rotblat J, Sharma R, Cheng Y, Zubair AS, Simpkins A, Li G, Kung J, Perez D, Heldner MR, Scutelnic A, von Martial R, Siepen B, Rothstein A, Khazaal O, Do D, Al Kasab S, Rahman LA, Mistry EA, Kerrigan D, Lafever H, Nguyen TN, Klein P, Aparicio HJ, Frontera JA, Kuohn L, Agarwal S, Stretz C, Kala N, ElJamal S, Chang A, Cutting S, Indraswari F, de Havenon A, Muddasani V, Wu T, Wilson D, Nouh A, Asad D, Qureshi A, Moore J, Khatri P, Aziz Y, Casteigne B, Khan M, Cheng Y, Grory BM, Weiss M, Ryan D, Vedovati MC, Paciaroni M, Siegler J, Kamen S, Yu S, Guerrero CL, Atallah E, De Marchis GM, Brehm A, Dittrich T, Psychogios M, Alvarado-Dyer R, Kass-Hout T, Prabhakaran S, Honda T, Liebeskind D, Furie K, Yaghi S. Predictors of Recurrent Venous Thrombosis After Cerebral Venous Thrombosis. Neurology 2022, 99: e2368-e2377. PMID: 36123126, PMCID: PMC9687409, DOI: 10.1212/wnl.0000000000201122.Peer-Reviewed Original ResearchConceptsCerebral venous thrombosisRecurrent venous thrombosisHistory of VTEVenous thrombosisVenous thromboembolismAntiphospholipid antibodiesBlack raceDiagnosis of CVTPositive antiphospholipid antibodiesRecurrent venous thrombosesAntiphospholipid antibody syndromeRecurrent venous thromboembolismCox regression analysisRisk of recurrenceMulticenter international studyAntibody syndromeOral anticoagulationVenous thrombosesConsecutive patientsRare causeMean ageTreatment strategiesThrombosisPatientsSecondary analysisIV tenecteplase: A non-inferior alternative to alteplase?
Zubair AS, Sheth KN. IV tenecteplase: A non-inferior alternative to alteplase? Med 2022, 3: 519-520. PMID: 35963230, DOI: 10.1016/j.medj.2022.07.006.Peer-Reviewed Original ResearchIntravenous Immune Globulins vs Plasma Exchange Usage in Patients with Neuromuscular and Neuro-immunological Conditions (P4-13.007)
Rethana M, Zubair A, Ma A, McAlpine L, Abulaban A, Nowak R, Roy B. Intravenous Immune Globulins vs Plasma Exchange Usage in Patients with Neuromuscular and Neuro-immunological Conditions (P4-13.007). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.2392.Peer-Reviewed Original Research
2021
Powassan Meningoencephalitis: A Case Report Highlighting Diagnosis and Management
Pach JJ, Zubair AS, Traner C, Falcone GJ, Dewey JJ, Traner C. Powassan Meningoencephalitis: A Case Report Highlighting Diagnosis and Management. Cureus 2021, 13: e16592. PMID: 34430178, PMCID: PMC8378285, DOI: 10.7759/cureus.16592.Peer-Reviewed Original ResearchEmergency Care of Patients with Acute Ischemic Stroke
Zubair AS, Sheth KN. Emergency Care of Patients with Acute Ischemic Stroke. Neurologic Clinics 2021, 39: 391-404. PMID: 33896525, DOI: 10.1016/j.ncl.2021.02.001.BooksConceptsAcute ischemic strokeIschemic strokeAcute ischemic stroke managementIschemic stroke managementLong-term disabilityEndovascular therapyStroke managementTreatment optionsLeading causePatient outcomesEmergency careGolden hourInitial evaluationMajor causeStrokeFirst hourPatientsCauseHoursThrombolysisMorbidityTherapyMortalityCare
2020
A critically ill patient with central nervous system tuberculosis and negative initial screening workup (2660)
Zubair A, Landreneau M, Witsch J, Fulbright R, Huttner A, Sheth K, Hwang D. A critically ill patient with central nervous system tuberculosis and negative initial screening workup (2660). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.2660.Peer-Reviewed Original Research
2014
Mo1280 Next Generation Sequencing of Gastric Smooth Muscle RNA Identifies Gene Markers for Altered Immune Function and Reduced Cellular Proliferation and Differentiation in Patients With Gastroparesis
Gibbons S, Bernard C, Zubair A, Boone K, Kendrick M, Shen K, Sarr M, Lombardo K, Consortium G, Parkman H, Pasricha P, Farrugia G. Mo1280 Next Generation Sequencing of Gastric Smooth Muscle RNA Identifies Gene Markers for Altered Immune Function and Reduced Cellular Proliferation and Differentiation in Patients With Gastroparesis. Gastroenterology 2014, 146: s-606. DOI: 10.1016/s0016-5085(14)62195-8.Peer-Reviewed Original Research