2024
Invited Perspective: Challenges and Opportunities in Evaluating the Effect of Chemical Mixtures on Congenital Chromosomal Abnormalities.
Liew Z, Guo P. Invited Perspective: Challenges and Opportunities in Evaluating the Effect of Chemical Mixtures on Congenital Chromosomal Abnormalities. Environmental Health Perspectives 2024, 132: 91301. PMID: 39258901, PMCID: PMC11389476, DOI: 10.1289/ehp15799.Peer-Reviewed Original ResearchExposure range matters: considering non-linear associations in the meta-analysis of environmental pollutant exposure using examples of per- and polyfluoroalkyl substances and birth outcomes
Guo P, Warren J, Deziel N, Liew Z. Exposure range matters: considering non-linear associations in the meta-analysis of environmental pollutant exposure using examples of per- and polyfluoroalkyl substances and birth outcomes. American Journal Of Epidemiology 2024, kwae309. PMID: 39227151, DOI: 10.1093/aje/kwae309.Peer-Reviewed Original ResearchNon-linear associationMeta-analysisHeterogeneity of effect estimatesEffect estimatesPotential non-linear associationsExposure-outcome relationshipsRisk of preterm birthSubgroup meta-analysisBirth outcomesPollution exposureMeta-analytic approachMeta-analysesEffect sizeEnvironmental pollutant exposureResults heterogeneityExposure levelsHealth effectsPreterm birthEvidence-based policymakingPrenatal exposurePotential heterogeneityMean birth weightBirth weightMethodological challengesCut-off choiceQuantitative bias analysis methods for summary-level epidemiologic data in the peer-reviewed literature: a systematic review
Shi X, Liu Z, Zhang M, Hua W, Li J, Lee J, Dharmarajan S, Nyhan K, Naimi A, Lash T, Jeffery M, Ross J, Liew Z, Wallach J. Quantitative bias analysis methods for summary-level epidemiologic data in the peer-reviewed literature: a systematic review. Journal Of Clinical Epidemiology 2024, 175: 111507. PMID: 39197688, DOI: 10.1016/j.jclinepi.2024.111507.Peer-Reviewed Original ResearchQuantitative bias analysis methodsQuantitative bias analysisPeer-reviewed literatureSystematic reviewEpidemiological dataObservational studyOpen Science FrameworkEnglish-language articlesWeb of ScienceMisclassification biasImpact of biasScience FrameworkStudy designEffect estimatesMeta-analysesPre-registeredStudy protocolBias analysisSelection biasLevel dataFuture investigationsMultiple biasesConfoundingReviewMEDLINEInvestigating Selection Bias in the Context of Multigenerational Cohort Study
Xiao J, Guo P, Li J, Liew Z. Investigating Selection Bias in the Context of Multigenerational Cohort Study. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0353.Peer-Reviewed Original ResearchMaternal Residential Mobility Between Pregnancies: A California Statewide Sibling Study
Bellia G, Zhuo H, Liew Z. Maternal Residential Mobility Between Pregnancies: A California Statewide Sibling Study. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0697.Peer-Reviewed Original ResearchPaternal and Maternal Exposures to Per- And Polyfluoroalkyl Substances and Child Behavioral Difficulties
Guo P, Luo J, Arah O, Toft G, Liew Z. Paternal and Maternal Exposures to Per- And Polyfluoroalkyl Substances and Child Behavioral Difficulties. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0321.Peer-Reviewed Original ResearchIs man the only animal with ears that cannot move them? Reflections on observational studies in obstetrics and gynecology
Pedersen L, Liew Z. Is man the only animal with ears that cannot move them? Reflections on observational studies in obstetrics and gynecology. Acta Obstetricia Et Gynecologica Scandinavica 2024, 103: 1478-1479. PMID: 39044537, PMCID: PMC11266722, DOI: 10.1111/aogs.14925.Peer-Reviewed Original ResearchFamily history of psychiatric conditions and development of siblings of children with autism
Bellia G, Chang J, Liew Z, Vernetti A, Macari S, Powell K, Chawarska K. Family history of psychiatric conditions and development of siblings of children with autism. Autism Research 2024, 17: 1665-1676. PMID: 38896553, PMCID: PMC11341253, DOI: 10.1002/aur.3175.Peer-Reviewed Original ResearchSiblings of childrenNeuropsychiatric disordersFamilies of childrenFamily history of schizophreniaYounger siblings of childrenHistory of psychiatric conditionsHistory of schizophreniaYounger siblingsAssess autism symptomsNonverbal IQAutism symptomsBipolar disorderIntellectual disabilityPsychiatric conditionsSubclinical symptomsAdaptive skillsSocial affectAdaptive functioningAutismFamily historyParent interviewsFamily factorsMultiple regression analysisDevelopmental outcomesDisordersAutism Spectrum Disorder and Grandmother’s Race, Ethnicity, and Nativity
Chow T, Meng Q, O’Sharkey K, Liew Z, Ritz B. Autism Spectrum Disorder and Grandmother’s Race, Ethnicity, and Nativity. JAACAP Open 2024 DOI: 10.1016/j.jaacop.2024.04.008.Peer-Reviewed Original ResearchIntellectual disabilityForeign-bornForeign-born whitesUS-born WhitesForeign-born blacksUS-born blacksForeign-born APIsUS-bornAsian-Pacific IslandersAutism spectrum disorderCalifornia DepartmentNativesGrandmothersPacific IslandersOdds ratioGrandchildrenEthnicityOffspring autism spectrum disorderRaceSelf-reported raceBirth certificatesMother-child pairsStudy investigated associationsWhitePublic healthMaternal intake of paracetamol during pregnancy and biomarkers of male fecundity in young adult sons
Laursen T, Ramlau-Hansen C, Tøttenborg S, Liew Z, Toft G, Gaml-Sørensen A, Hougaard K, Bonde J, Ernst A. Maternal intake of paracetamol during pregnancy and biomarkers of male fecundity in young adult sons. Reproductive Toxicology 2024, 127: 108626. PMID: 38815769, DOI: 10.1016/j.reprotox.2024.108626.Peer-Reviewed Original ResearchIntake of paracetamolMaternal intakeHigher DNA fragmentation indexDanish National Birth CohortDNA fragmentation indexSemen characteristicsLong durationImpaired semen qualityConfidence intervalsImpaired semen characteristicsNational Birth CohortReproductive hormone levelsAssociated with biomarkersDuration of exposureYears of ageFetal programmingNo intakeImmotile spermatozoaSons of mothersFollow-upYoung adult menHormone levelsSemen qualityMale fecundityTrimester-specificMediating Factors in the Association of Maternal Educational Level With Pregnancy Outcomes
Rogne T, Gill D, Liew Z, Shi X, Stensrud V, Nilsen T, Burgess S. Mediating Factors in the Association of Maternal Educational Level With Pregnancy Outcomes. JAMA Network Open 2024, 7: e2351166. PMID: 38206626, PMCID: PMC10784860, DOI: 10.1001/jamanetworkopen.2023.51166.Peer-Reviewed Original ResearchMeSH KeywordsBirth WeightCholesterolCohort StudiesDiabetes Mellitus, Type 2Educational StatusFemaleGenome-Wide Association StudyHumansHyperemesis GravidarumInfant, NewbornLipoproteins, HDLMediation AnalysisMendelian Randomization AnalysisPre-EclampsiaPregnancyPregnancy OutcomePregnancy, EctopicPremature BirthConceptsCardiometabolic risk factorsBody mass indexOffspring birth weightEducational attainmentMendelian randomizationHigh-density lipoprotein cholesterol levelsSystolic blood pressureInverse variance-weighted methodModifiable cardiometabolic risk factorsPregnancy outcomesCohort studyLipoprotein cholesterol levelsMR-Egger regressionMass indexUnivariable MR analysisEffects of educational attainmentAssociated with increased risk of adverse pregnancy outcomesPublic health interventionsMaternal education levelLower educational attainmentRisk factorsRisk of adverse pregnancy outcomesGenome-wide association studiesAssociated with increased riskBirth weight
2023
Association Between Estimated Geocoded Residential Maternal Exposure to Lithium in Drinking Water and Risk for Autism Spectrum Disorder in Offspring in Denmark
Liew Z, Meng Q, Yan Q, Schullehner J, Hansen B, Kristiansen S, Voutchkova D, Olsen J, Ersbøll A, Ketzel M, Raaschou-Nielsen O, Ritz B. Association Between Estimated Geocoded Residential Maternal Exposure to Lithium in Drinking Water and Risk for Autism Spectrum Disorder in Offspring in Denmark. Obstetrical & Gynecological Survey 2023, 78: 713-715. DOI: 10.1097/ogx.0000000000001228.Peer-Reviewed Original ResearchA scoping review of multigenerational impacts of grandparental exposures on mental health in grandchildren
Xiao J, Jain A, Bellia G, Nyhan K, Liew Z. A scoping review of multigenerational impacts of grandparental exposures on mental health in grandchildren. Current Environmental Health Reports 2023, 10: 369-382. PMID: 38008881, DOI: 10.1007/s40572-023-00413-8.Peer-Reviewed Original ResearchMental healthGrandparental ageAdverse delivery outcomesPregnancy-related factorsUse of diethylstilbestrolNeurodevelopmental disordersCurrent epidemiological studiesAttention-deficit/hyperactivity disorderMental health outcomesMedication intakeDelivery outcomesEpidemiological studiesHealth StudyHealth outcomesPregnancyBiological markersLiterature searchRecent FindingsWeHyperactivity disorderOutcome phenotypesSocial environmental stressorsDisordersExposure assessmentOutcomesMultigenerational effectsReevaluating the Association Between Autism and Lithium Exposure During Pregnancy—Reply
Liew Z, Raaschou-Nielsen O, Ritz B. Reevaluating the Association Between Autism and Lithium Exposure During Pregnancy—Reply. JAMA Pediatrics 2023, 177: 1241-1242. PMID: 37782480, DOI: 10.1001/jamapediatrics.2023.3954.Peer-Reviewed Original ResearchMaternal medically diagnosed infection and antibiotic prescription during pregnancy and risk of childhood cancer: A population‐based cohort study in Taiwan, 2004 to 2015
Sirirungreung A, Lee P, Hu Y, Liew Z, Ritz B, Heck J. Maternal medically diagnosed infection and antibiotic prescription during pregnancy and risk of childhood cancer: A population‐based cohort study in Taiwan, 2004 to 2015. International Journal Of Cancer 2023, 154: 626-635. PMID: 37792464, PMCID: PMC10942658, DOI: 10.1002/ijc.34744.Peer-Reviewed Original ResearchConceptsPopulation-based cohort studyMaternal infectionAcute lymphoblastic leukemiaAntibiotic prescriptionsChildhood cancerCohort studyChildhood acute lymphoblastic leukemiaChild Health DatabaseRisk of hepatoblastomaProportional hazards modelMother-child pairsMedian followTaiwan MaternalCancer RegistryLymphoblastic leukemiaAntibiotic useNational HealthAntibiotic exposureElevated riskHigh riskHazards modelPregnancyChildhood leukemiaHealth databasesChildhood hepatoblastomaPrenatal Exposure to Toxic Air Contaminants and the Risk for Cerebral Palsy
Zhuo H, Ritz B, Liew Z. Prenatal Exposure to Toxic Air Contaminants and the Risk for Cerebral Palsy. ISEE Conference Abstracts 2023, 2023 DOI: 10.1289/isee.2023.op-046.Peer-Reviewed Original ResearchLithium in Drinking Water and Autism Spectrum Disorder
Liew Z, Meng Q, Yan Q, Schullehner J, Hansen B, Kristiansen S, Voutchkova D, Olsen J, Ersbøll A, Ketzel M, Nielsen O, Ritz B. Lithium in Drinking Water and Autism Spectrum Disorder. ISEE Conference Abstracts 2023, 2023 DOI: 10.1289/isee.2023.op-075.Peer-Reviewed Original ResearchPer- and polyfluoroalkyl substances and sleep health in U.S. adults, NHANES 2005–2014
Guo P, Jin Z, Bellia G, Luo J, Inoue K, Pollitt K, Deziel N, Liew Z. Per- and polyfluoroalkyl substances and sleep health in U.S. adults, NHANES 2005–2014. Environmental Research 2023, 237: 117092. PMID: 37683785, DOI: 10.1016/j.envres.2023.117092.Peer-Reviewed Original ResearchSleep disordersSleep outcomesU.S. adultsNHANES 2005Inverse associationSleep durationSerum polyfluoroalkyl substancesCentral nervous systemSerum concentration dataDaily sleep durationExposure tertilesOxidative inflammatory responseQuartile increaseBias analysisInflammatory responseExcessive sleepUncontrolled confoundingNervous systemSleep healthPFAS exposureHealth measuresQuantitative bias analysisLogistic regressionConsistent associationDisordersSeason of Conception and Risk of Cerebral Palsy
Zhuo H, Ritz B, Warren J, Liew Z. Season of Conception and Risk of Cerebral Palsy. JAMA Network Open 2023, 6: e2335164. PMID: 37738049, PMCID: PMC10517373, DOI: 10.1001/jamanetworkopen.2023.35164.Peer-Reviewed Original ResearchConceptsCerebral palsySeason of conceptionCalifornia birth recordsCohort studyPreterm birthRelative riskBirth recordsRisk of CPStatewide cohort studyEtiological risk factorsHigher Social Vulnerability IndexLength of gestationDiagnostic recordsNeighborhood-level factorsSummer conceptionsRisk factorsStratified analysisLive birthsMAIN OUTCOMEHigh riskCP riskPoisson regressionCP statusDevelopmental servicesNeuromotor disabilitiesAntithyroid drug exposure during 1,191,904 pregnancies in denmark: a 20-year longitudinal study before and after implementation of iodine fortification
Maria U, Liew Z, Carle A, Scott K, Bulow P, Andersen S, Linding A. Antithyroid drug exposure during 1,191,904 pregnancies in denmark: a 20-year longitudinal study before and after implementation of iodine fortification. Endocrine Abstracts 2023 DOI: 10.1530/endoabs.92.op-06-01.Peer-Reviewed Original Research