2012
Large Scale Association Analysis for Drug Addiction: Results from SNP to Gene
Guo X, Liu Z, Wang X, Zhang H. Large Scale Association Analysis for Drug Addiction: Results from SNP to Gene. The Scientific World JOURNAL 2012, 2012: 939584. PMID: 23365539, PMCID: PMC3543790, DOI: 10.1100/2012/939584.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsChromosome MappingGenetic Predisposition to DiseaseGenome, HumanGenome-Wide Association StudyHumansModels, GeneticPolymorphism, Single NucleotideSubstance-Related DisordersConceptsGenome-wide association studiesAssociation studiesAssociation analysisGene-based association analysisLarge-scale association analysisSingle nucleotide polymorphism dataWide association studyComplex diseasesGene-based analysisGene-based methodsNucleotide polymorphism dataGenetic association studiesPolymorphism dataGene findingGenetic variantsIndividual SNPsStudy of AddictionSNPsGenetic etiologyGenesComprehensive analysisGeneticsVariantsGenetic Association Test for Multiple Traits at Gene Level
Guo X, Liu Z, Wang X, Zhang H. Genetic Association Test for Multiple Traits at Gene Level. Genetic Epidemiology 2012, 37: 122-129. PMID: 23032486, PMCID: PMC3524409, DOI: 10.1002/gepi.21688.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesMultiple traitsGene levelSingle nucleotide polymorphismsGenetic association testsCommon genesAssociation studiesAssociation TestNucleotide polymorphismsTraitsStudy of AddictionComplex diseasesBiological mechanismsDisease of interestAssociation informationGenesGeneticsSuch studiesStrong evidencePolymorphismPrevious findingsLevels
2011
The Nuclear Transcription Factor PKNOX2 Is a Candidate Gene for Substance Dependence in European-Origin Women
Chen X, Cho K, Singer BH, Zhang H. The Nuclear Transcription Factor PKNOX2 Is a Candidate Gene for Substance Dependence in European-Origin Women. PLOS ONE 2011, 6: e16002. PMID: 21298047, PMCID: PMC3029286, DOI: 10.1371/journal.pone.0016002.Peer-Reviewed Original Research
2006
Substance-abusing mothers and disruptions in child custody: An attachment perspective
Suchman NE, McMahon TJ, Zhang H, Mayes LC, Luthar S. Substance-abusing mothers and disruptions in child custody: An attachment perspective. Journal Of Substance Use And Addiction Treatment 2006, 30: 197-204. PMID: 16616163, PMCID: PMC1850760, DOI: 10.1016/j.jsat.2005.11.008.Peer-Reviewed Original ResearchConceptsAttachment perspectiveInternal psychological processesMothers' perceptionsParental Bonding InstrumentSubstance-abusing mothersPsychological maladjustmentPsychological processesMultilevel modeling approachAttachment frameworkAddiction Severity IndexSubstance abuseChild placementDemographic questionnaireChild custodyPerceptionComposite scoreMethadone maintenance programMaladjustmentParentingMothersAbuseParentsPerspectiveSeverity IndexChildren
2004
Results of a genomewide linkage scan: Support for chromosomes 9 and 11 loci increasing risk for cigarette smoking
Gelernter J, Liu X, Hesselbrock V, Page GP, Goddard A, Zhang H. Results of a genomewide linkage scan: Support for chromosomes 9 and 11 loci increasing risk for cigarette smoking. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2004, 128B: 94-101. PMID: 15211640, DOI: 10.1002/ajmg.b.30019.Peer-Reviewed Original Research
2003
Developmental Trajectories of Cocaine-and-Other-Drug—Exposed and Non-Cocaine—Exposed Children
MAYES LC, CICCHETTI D, ACHARYYA S, ZHANG H. Developmental Trajectories of Cocaine-and-Other-Drug—Exposed and Non-Cocaine—Exposed Children. Journal Of Developmental And Behavioral Pediatrics 2003, 24: 323-335. PMID: 14578693, DOI: 10.1097/00004703-200310000-00003.Peer-Reviewed Original ResearchMeSH KeywordsChildChild DevelopmentCocaineFemaleHumansInfantMental ProcessesMotor SkillsPregnancyPrenatal Exposure Delayed EffectsSubstance-Related DisordersTime FactorsConceptsCocaine-exposed childrenMental performanceMotor developmentDrug-exposed childrenInfant Development IICocaine-exposed groupDevelopmental trajectoriesBayley ScalesDevelopment IIMotor performanceAssessment ageComparison groupDevelopmental IndexChildrenCocaineCurve analysisGreater decreaseInfantsTrajectoriesPerformanceGeneral declineMonthsDrugsAgeGroupAssessing Sex Differences on Treatment Effectiveness from the Drug Abuse Treatment Outcome Study (DATOS)
Acharyya S, Zhang H. Assessing Sex Differences on Treatment Effectiveness from the Drug Abuse Treatment Outcome Study (DATOS). The American Journal Of Drug And Alcohol Abuse 2003, 29: 415-444. PMID: 12765214, DOI: 10.1081/ada-120020524.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultDemographyFemaleHumansMaleOutcome Assessment, Health CareSeverity of Illness IndexSex FactorsSubstance Abuse Treatment CentersSubstance-Related DisordersTreatment OutcomeConceptsDrug Abuse Treatment Outcome StudyTreatment modalitiesTreatment effectivenessDrug treatment programsEffects of drugsTreatment outcome studiesClinical differencesTreatment successOutcome studiesTreatment programSeverity IndexDemographic characteristicsWomenDemographic covariatesSex differencesSexMenCumulative logit modelModalitiesGender-based variation
2002
The spectrum of social phobia in the zurich cohort study of young adults
Merikangas KR, Avenevoli S, Acharyya S, Zhang H, Angst J. The spectrum of social phobia in the zurich cohort study of young adults. Biological Psychiatry 2002, 51: 81-91. PMID: 11801233, DOI: 10.1016/s0006-3223(01)01309-9.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge of OnsetCatchment Area, HealthCognitive Behavioral TherapyCohort StudiesComorbidityCuesFemaleHumansInterpersonal RelationsMalePersonalityPhobic DisordersPrevalencePsychiatric Status Rating ScalesSeverity of Illness IndexSocial PerceptionSubstance-Related DisordersSwitzerlandTemperamentConceptsDiagnostic thresholdProspective-longitudinal community studySocial phobiaYoung adultsZurich cohort studyHigher lifetime ratesLongitudinal community studyPercent of participantsSocial phobia symptomsCohort studyMedication useStudy entryWork impairmentClinical indicatorsRisk factorsUndiagnosed casesFamily historyEqual gender ratioAge 35Phobia symptomsGeneral populationLifetime ratesLongitudinal courseTreatment ratesCommunity study
1998
Familial Transmission of Substance Use Disorders
Merikangas KR, Stolar M, Stevens DE, Goulet J, Preisig MA, Fenton B, Zhang H, O'Malley SS, Rounsaville BJ. Familial Transmission of Substance Use Disorders. JAMA Psychiatry 1998, 55: 973-979. PMID: 9819065, DOI: 10.1001/archpsyc.55.11.973.Peer-Reviewed Original ResearchConceptsSubstance use disordersAdult first-degree relativesFirst-degree relativesDrug disordersRisk factorsUse disordersPredominant drugFamilial aggregationPotent risk factorRelatives of probandsAntisocial personality disorderFamily history interviewSubstance disordersFamily historyControl probandsDiagnostic InterviewOpioidsPersonality disorderDisordersFamilial transmissionGenetic factorsProbandsCocaineDrugsCannabis