1987
Coexistence of GABA receptors and GABA-modulin in primary cultures of rat cerebellar granule cells
Vaccarino FM, Alho H, Santi MR, Guidotti A. Coexistence of GABA receptors and GABA-modulin in primary cultures of rat cerebellar granule cells. Journal Of Neuroscience 1987, 7: 65-76. PMID: 3027277, PMCID: PMC6568852, DOI: 10.1523/jneurosci.07-01-00065.1987.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarrier ProteinsCells, CulturedCerebellumFlunitrazepamFluorescent Antibody TechniqueGABA Plasma Membrane Transport ProteinsGamma-Aminobutyric AcidHistocytochemistryMembrane ProteinsMembrane Transport ProteinsMuscimolNerve Tissue ProteinsOrganic Anion TransportersRadioimmunoassayRatsReceptors, GABA-ASynaptosomesConceptsRat brain synaptosomesGranule cell culturesBrain synaptosomesGranule cellsGABA-modulinPrimary culturesCerebellar granule cell culturesRat cerebellar granule cellsPurkinje cell dendritesGranular cell layerGABA receptor complexGABA recognition siteCerebellar granule cellsGABAergic neuronsGABAergic interneuronsCell dendritesGlial cellsGABA receptorsIntact cell monolayersCell membrane preparationsCell culturesCerebellar interneuronsCell bodiesSpecific antibodiesSynaptosomes
1985
Residual benzodiazepine (BZ) binding in the cortex ofpcd mutant cerebella and qualitative BZ binding in the deep cerebellar nuclei of control and mutant mice: an autoradiographic study
Vaccarino F, Ghetti B, Nurnberger J. Residual benzodiazepine (BZ) binding in the cortex ofpcd mutant cerebella and qualitative BZ binding in the deep cerebellar nuclei of control and mutant mice: an autoradiographic study. Brain Research 1985, 343: 70-78. PMID: 2994831, DOI: 10.1016/0006-8993(85)91159-x.Peer-Reviewed Original Research
1983
GABAergic synapses supramolecular organization and biochemical regulation
Guidotti A, Corda MG, Wise BC, Vaccarino F, Costa E. GABAergic synapses supramolecular organization and biochemical regulation. Neuropharmacology 1983, 22: 1471-1479. PMID: 6322041, DOI: 10.1016/0028-3908(83)90115-6.Peer-Reviewed Original ResearchConceptsProtein kinaseCyclic AMP-dependent protein kinaseAMP-dependent protein kinaseBasic proteinDependent protein kinaseCyclic AMP-dependent phosphorylationRecognition sitesGABA-modulinMyelin basic proteinAmino acid compositionBiochemical regulationMolecular mechanismsHigh-affinity bindingPostsynaptic neuronal membranesProteinLoss of Purkinje cell‐associated benzodiazepine receptors spares a high affinity subpopulation: A study with pcd mutant mice
Vaccarino FM, Ghetti B, Wade SE, Rea MA, Aprison MH. Loss of Purkinje cell‐associated benzodiazepine receptors spares a high affinity subpopulation: A study with pcd mutant mice. Journal Of Neuroscience Research 1983, 9: 311-323. PMID: 6304330, DOI: 10.1002/jnr.490090308.Peer-Reviewed Original ResearchConceptsPopulation of receptorsBZ receptorsBenzodiazepine receptorsPurkinje cellsMutant miceHigh affinity subpopulationPcd miceGranule cell lossPurkinje cell degeneration mutant micePcd mutant miceNumber of receptorsDays of ageControl miceGlial cellsGranule cellsCell lossMicePcd mutantsReceptorsLow affinity sitesRegression analysisAgeDaysCellsSaturation data