2018
Conscious status is associated with the likelihood of trauma centre care and mortality in patients with moderate-to-severe traumatic brain injury
AlSulaim H, Haring R, Asemota A, Smart B, Canner J, Ejaz A, Efron D, Velopulos C, Haut E, Schneider E. Conscious status is associated with the likelihood of trauma centre care and mortality in patients with moderate-to-severe traumatic brain injury. Brain Injury 2018, 32: 784-793. PMID: 29561720, DOI: 10.1080/02699052.2018.1451658.Peer-Reviewed Original ResearchConceptsLoss of consciousnessNon-trauma centersTraumatic brain injuryTrauma centerBrain injuryHead/neck Abbreviated Injury Scale scoreNeck Abbreviated Injury Scale scoreLevel I/II trauma centersAbbreviated Injury Scale scoreSevere traumatic brain injuryInjury Scale scoreOdds of mortalityTrauma center careTC treatmentLogistic regression modelsHospital mortalityOlder patientsPatient demographicsPrimary outcomeInjury characteristicsNinth RevisionAIS scoreTBI outcomesPrevention criteriaClinical ModificationThe “mortality ascent”
Herrera-Escobar JP, Rios-Diaz AJ, Zogg CK, Wolf LL, Harlow A, Schneider EB, Cooper Z, Ordonez CA, Salim A, Haider AH. The “mortality ascent”. Journal Of Trauma And Acute Care Surgery 2018, 84: 139-145. PMID: 28930947, DOI: 10.1097/ta.0000000000001706.Peer-Reviewed Original ResearchConceptsUnstable trauma patientsLevel I TCsLevel II TCsHours postadmissionTrauma patientsLevel ILevel IIMortality riskHospital mortalityLog-binomial regression modelsNational Trauma Data BankComparable mortality riskHospital-level confoundersInjury Severity ScoreSystolic blood pressureAvailable treatment modalitiesTrauma Data BankSpecific risk factorsRisk-adjusted modelsBlood pressureHigher relative mortalityUnstable patientsBurn patientsSeverity scoreTreatment modalities
2016
Validation of international trauma scoring systems in urban trauma centres in India
Roy N, Gerdin M, Schneider E, Veetil D, Khajanchi M, Kumar V, Saha M, Dharap S, Gupta A, Tomson G, von Schreeb J. Validation of international trauma scoring systems in urban trauma centres in India. Injury 2016, 47: 2459-2464. PMID: 27667119, DOI: 10.1016/j.injury.2016.09.027.Peer-Reviewed Original ResearchConceptsInjury Severity ScoreTrauma Injury Severity ScoreKampala Trauma ScoreTrauma patientsCasualty departmentPhysiological scoreTrauma centerSeverity scoreProspective multi-centre observational cohort studyMulti-center observational cohort studyInjury Severity Scale scoreAdult trauma patientsObservational cohort studySeverity Scale scoreUrban trauma centerHistory of injuryIncome country settingsMiddle-income country settingsHospital mortalityLate mortalityUrban Indian settingAdult patientsCohort studyInpatient mortalityPhysiologic scoreIntensity of treatment, end-of-life care, and mortality for older patients with severe traumatic brain injury
Lilley E, Williams K, Schneider E, Hammouda K, Salim A, Haider A, Cooper Z. Intensity of treatment, end-of-life care, and mortality for older patients with severe traumatic brain injury. Journal Of Trauma And Acute Care Surgery 2016, 80: 998-1004. PMID: 26953761, DOI: 10.1097/ta.0000000000001028.Peer-Reviewed Original ResearchConceptsSevere traumatic brain injuryTraumatic brain injuryGeriatric patientsFunctional statusBrain injuryHospital mortality outcomesPatients 65 yearsDays of injuryGoals of careFurther aggressive treatmentSurgery of TraumaIntensity of treatmentHospital mortalityHospital deathLife decision makingAggressive treatmentHospital dischargeIdentifies patientsNeurologic statusNonresponder groupOlder patientsRetrospective reviewMortality outcomesPoor prognosisFunctional impairment“Halo effect” in trauma centers: does it extend to emergent colectomy?
Nagarajan N, Selvarajah S, Gani F, Alshaikh HN, Giuliano K, Zogg CK, Schneider EB, Haider AH. “Halo effect” in trauma centers: does it extend to emergent colectomy? Journal Of Surgical Research 2016, 203: 231-237. PMID: 27125867, DOI: 10.1016/j.jss.2016.01.037.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overColectomyDatabases, FactualDiverticulitis, ColonicEmergenciesFemaleHospital ChargesHospital MortalityHumansLength of StayLinear ModelsLogistic ModelsMaleMiddle AgedPoisson DistributionQuality Assurance, Health CareQuality Indicators, Health CareTrauma CentersTreatment OutcomeUnited StatesYoung AdultConceptsLength of stayNontrauma centersHospital-level characteristicsTrauma centerEmergent colectomyEmergency general surgery conditionsEmergency general surgery proceduresNationwide Emergency Department SampleEmergency surgical interventionOdds of mortalityEmergency Department SampleGeneral surgery proceduresNontrauma conditionsHospital mortalityMedian ageSurgical interventionSurgical conditionsImproved outcomesSex distributionSurgical careMedian chargePatientsSurgery proceduresSurgery conditionsCase mix
2015
Socioeconomic correlates of trauma: An analysis of emergency ward patients in Yaoundé, Cameroon
Kacker S, Bishai D, Mballa G, Monono M, Schneider E, Ngamby K, Hyder A, Juillard C. Socioeconomic correlates of trauma: An analysis of emergency ward patients in Yaoundé, Cameroon. Injury 2015, 47: 658-664. PMID: 26763297, DOI: 10.1016/j.injury.2015.12.011.Peer-Reviewed Original ResearchConceptsLowest SES quintileSocioeconomic statusTrauma centerTreatment outcomesInjury severitySevere injuriesSES quintilesWealth scoreEmergency ward patientsLargest trauma hospitalMajor trauma centreCare-seeking behaviorFuture trauma researchSeverity of injuryRoad traffic injuriesHigher socioeconomic statusEffect of SESProspective registryTrauma patientsWard patientsCentral HospitalInjury characteristicsTrauma hospitalEmergency wardTrauma outcomesTraumatic Spinal Cord Injury Emergency Service Triage Patterns and the Associated Emergency Department Outcomes
Selvarajah S, Haider A, Schneider E, Sadowsky C, Becker D, Hammond E. Traumatic Spinal Cord Injury Emergency Service Triage Patterns and the Associated Emergency Department Outcomes. Journal Of Neurotrauma 2015, 32: 2008-2016. PMID: 26102350, DOI: 10.1089/neu.2015.4016.Peer-Reviewed Original ResearchConceptsAcute traumatic spinal cord injuryTraumatic spinal cord injuryNew Injury Severity ScoreNon-trauma centersEmergency department outcomesTrauma centerED mortalityLevel INationwide Emergency Department SampleInjury Severity ScoreEmergency Department SampleSpinal cord injuryTrauma patientsInjury characteristicsCord injurySeverity scorePatient experiencePatientsTriage practicesSevere injuriesTriage patternsAdult ageTriageHigher likelihoodOutcomesMilitary-to-civilian translation of battlefield innovations in operative trauma care
Haider AH, Piper LC, Zogg CK, Schneider EB, Orman JA, Butler FK, Gerhardt RT, Haut ER, Mather JP, MacKenzie EJ, Schwartz DA, Geyer DW, DuBose JJ, Rasmussen TE, Blackbourne LH. Military-to-civilian translation of battlefield innovations in operative trauma care. Surgery 2015, 158: 1686-1695. PMID: 26210224, DOI: 10.1016/j.surg.2015.06.026.Peer-Reviewed Original ResearchA modified Kampala trauma score (KTS) effectively predicts mortality in trauma patients
Weeks S, Stevens K, Haider A, Efron D, Haut E, MacKenzie E, Schneider E. A modified Kampala trauma score (KTS) effectively predicts mortality in trauma patients. Injury 2015, 47: 125-129. PMID: 26256783, DOI: 10.1016/j.injury.2015.07.004.Peer-Reviewed Original ResearchConceptsNew Injury Severity ScoreInjury Severity ScoreKampala Trauma ScoreTrauma patientsSeverity scoreTrauma ScorePhysiologic measuresMortality predictionNon-trauma center hospitalsSeverity scoring toolsPre-hospital intubationCenter HospitalInjury scoreAnatomical injuryMortality riskLevel IInjury severityRespiratory ratePhysiologic dataScoring toolOutcome predictionMortalitySignificant predictorsCharacteristic curveSimilar predictive abilityInvestigating the relationship between weather and violence in Baltimore, Maryland, USA
Michel S, Wang H, Selvarajah S, Canner J, Murrill M, Chi A, Efron D, Schneider E. Investigating the relationship between weather and violence in Baltimore, Maryland, USA. Injury 2015, 47: 272-276. PMID: 26233631, DOI: 10.1016/j.injury.2015.07.006.Peer-Reviewed Original ResearchDo trauma center levels matter in older isolated hip fracture patients?
Nelson-Williams H, Kodadek L, Canner J, Schneider E, Efron D, Haut E, Shafiq B, Haider A, Velopulos CG. Do trauma center levels matter in older isolated hip fracture patients? Journal Of Surgical Research 2015, 198: 468-474. PMID: 26038246, DOI: 10.1016/j.jss.2015.03.074.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overFemaleHip FracturesHumansMaleRetrospective StudiesTrauma CentersUnited StatesConceptsHip fracture patientsLevel trauma centerTrauma center levelFracture patientsTrauma centerDischarge dispositionUnadjusted logistic regression analysisNationwide Emergency Department SampleHigh-level trauma centersLower level trauma centerIsolated hip fractureHospital-level factorsOdds of dischargeOdds of mortalityHospital-level variablesMulti-trauma patientsMultivariable logistic regressionEmergency Department SampleMain outcome measuresLogistic regression analysisCenter levelInhospital mortalityOlder patientsRetrospective cohortHip fractureOutcomes of trauma care at centers treating a higher proportion of older patients
Zafar S, Obirieze A, Schneider E, Hashmi Z, Scott V, Greene W, Efron D, MacKenzie E, Cornwell E, Haider A. Outcomes of trauma care at centers treating a higher proportion of older patients. Journal Of Trauma And Acute Care Surgery 2015, 78: 852-859. PMID: 25742246, DOI: 10.1097/ta.0000000000000557.Peer-Reviewed Original ResearchConceptsOlder trauma patientsOlder patientsTrauma patientsTrauma centerLevel 2 trauma centerMultivariate logistic regression modelRisk-adjusted mortality ratioYoung adultsGeriatric trauma patientsAdult trauma patientsBurden of injuryLength of stayObserved-expected ratioTrauma center performanceHigher proportionLogistic regression modelsGeriatric traumaYounger patientsTrauma deathsMortality ratioTrauma visitsTrauma careEpidemiologic studiesPatientsBetter outcomes
2014
Increased mortality associated with EMS transport of gunshot wound victims when compared to private vehicle transport
Zafar S, Haider A, Stevens K, Ray-Mazumder N, Kisat M, Schneider E, Chi A, Galvagno S, Cornwell E, Efron D, Haut E. Increased mortality associated with EMS transport of gunshot wound victims when compared to private vehicle transport. Injury 2014, 45: 1320-1326. PMID: 24957424, DOI: 10.1016/j.injury.2014.05.032.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAmbulancesAutomobilesEmergency Medical ServicesFemaleFluid TherapyGravity SuitsHospital MortalityHumansImmobilizationInjury Severity ScoreIntubation, IntratrachealMaleMiddle AgedMonitoring, PhysiologicOutcome and Process Assessment, Health CareRetrospective StudiesTime FactorsTransportation of PatientsTrauma CentersUnited StatesWounds, GunshotConceptsEmergency medical servicesProportion of patientsGSW patientsTrauma centerGunshot woundsNational Trauma Data BankGunshot wound victimsTrauma Data BankIndividual trauma centersMultivariable regression analysisHospital mortalityPatient demographicsUnadjusted mortalityTrauma patientsMultivariable analysisTwofold oddsEMS transportMortality differencesPatientsInjury severityPrivate vehicle transportMortalityWide variationMedical servicesFurther studiesBenchmarking of Trauma Care Worldwide: The Potential Value of an International Trauma Data Bank (ITDB)
Haider A, Hashmi Z, Gupta S, Zafar S, David J, Efron D, Stevens K, Zafar H, Schneider E, Voiglio E, Coimbra R, Haut E. Benchmarking of Trauma Care Worldwide: The Potential Value of an International Trauma Data Bank (ITDB). World Journal Of Surgery 2014, 38: 1882-1891. PMID: 24817407, DOI: 10.1007/s00268-014-2629-5.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBenchmarkingDatabases, FactualDeveloped CountriesDeveloping CountriesFeasibility StudiesFemaleFranceGlobal HealthHospital MortalityHumansLogistic ModelsMaleMiddle AgedPakistanRegistriesTrauma CentersWounds, NonpenetratingWounds, PenetratingYoung AdultConceptsTrauma Data BankTrauma mortalityTrauma centerMortality ratioTrauma outcomesNational Trauma Data BankTrauma dataE mortality ratioNational Trauma RegistryMultivariable logistic regressionBlunt/Worse survivalTrauma registrySubset analysisPatient outcomesTrauma carePatientsLMIC centerLogistic regressionKey covariatesOutcomesInjuryMortalityPredictorsSimilar resultsBenchmarking trauma centers on mortality alone does not reflect quality of care
Hashmi Z, Schneider E, Castillo R, Haut E, Zafar S, Cornwell E, MacKenzie E, Latif A, Haider A. Benchmarking trauma centers on mortality alone does not reflect quality of care. Journal Of Trauma And Acute Care Surgery 2014, 76: 1184-1191. PMID: 24747447, DOI: 10.1097/ta.0000000000000215.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBenchmarkingCause of DeathDatabases, FactualFemaleHealth Care SurveysHospital MortalityHumansInjury Severity ScoreMaleMiddle AgedQuality of Health CareReimbursement, IncentiveRisk AdjustmentSensitivity and SpecificitySurvival AnalysisTrauma CentersUnited StatesWounds and InjuriesWounds, NonpenetratingWounds, PenetratingYoung AdultConceptsInjury Severity ScoreTrauma centerNational Trauma Data BankPatients 16 yearsHigh complication rateRisk of deathTrauma Data BankHospital performance rankingsQuality of careUnadjusted morbidityPerformance statusComplication rateMajor complicationsMorbidity outcomesMortality outcomesSeverity scoreMorbidity ratioMortality ratioEpidemiologic studiesMorbidityMorbidity analysisMortality rateLevel IIIPoor concordanceComplicationsDeveloping best practices to study trauma outcomes in large databases
Haider A, Hashmi Z, Zafar S, Castillo R, Haut E, Schneider E, Cornwell E, Mackenzie E, Efron D. Developing best practices to study trauma outcomes in large databases. Journal Of Trauma And Acute Care Surgery 2014, 76: 1061-1069. PMID: 24662872, DOI: 10.1097/ta.0000000000000182.Peer-Reviewed Original ResearchConceptsNational Trauma Data BankRisk-adjustment modelsTrauma mortalityTrauma outcomesSubsequent multivariate logistic regression analysisMultivariate logistic regression analysisManual backward selectionTrauma Data BankUnivariate logistic regressionLogistic regression analysisInitial multivariate modelPatient subsetsMultivariable analysisTrauma centerMortality outcomesSimilar AUROCsSubset analysisUnivariate analysisPrognostic studiesAnalytic standardizationLevel IIILogistic regression
2013
Venous Thromboembolism After Trauma: When Do Children Become Adults?
Van Arendonk K, Schneider E, Haider A, Colombani P, Stewart F, Haut E. Venous Thromboembolism After Trauma: When Do Children Become Adults? JAMA Surgery 2013, 148: 1123-1130. PMID: 24173244, DOI: 10.1001/jamasurg.2013.3558.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsChildChild, PreschoolCohort StudiesConfidence IntervalsDatabases, FactualFemaleHospitalizationHumansIncidenceInfantMaleOdds RatioPrognosisRetrospective StudiesRisk AssessmentTrauma CentersTrauma Severity IndicesTreatment OutcomeUnited StatesVenous ThromboembolismWounds and InjuriesYoung AdultConceptsRisk of VTEVenous thromboembolismPediatric traumaTrauma centerStandardized guidelinesNational Trauma Data BankMultivariable logistic regression modelDiagnosis of VTENational standardized guidelinesOdds of VTEPatients 16 yearsPatients 21 yearsVenous thromboembolism prophylaxisVTE risk factorsPatients 12 yearsTrauma Data BankUS trauma centersAge 16 yearsCentral line placementAge 13 yearsLogistic regression modelsThromboembolism prophylaxisVTE prophylaxisPatient ageYounger patientsMinority Trauma Patients Tend to Cluster at Trauma Centers with Worse-Than-Expected Mortality
Haider A, Hashmi Z, Zafar S, Hui X, Schneider E, Efron D, Haut E, Cooper L, MacKenzie E, Cornwell E. Minority Trauma Patients Tend to Cluster at Trauma Centers with Worse-Than-Expected Mortality. Annals Of Surgery 2013, 258: 572-581. PMID: 23979271, PMCID: PMC5995334, DOI: 10.1097/sla.0b013e3182a50148.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBlack or African AmericanDatabases, FactualFemaleHealth Status DisparitiesHealthcare DisparitiesHispanic or LatinoHospital MortalityHumansInjury Severity ScoreLogistic ModelsMaleMiddle AgedMinority HealthMultivariate AnalysisOutcome Assessment, Health CareTrauma CentersUnited StatesWhite PeopleWounds, NonpenetratingWounds, PenetratingYoung AdultConceptsTrauma centerNational Trauma Data Bank 2007High mortalityLevel I/II trauma centersPatient/injury characteristicsE mortality ratioPatients 16 yearsInjury Severity ScoreMultivariate logistic regressionIndividual trauma centersNumber of deathsBlunt/Trauma patientsBlack patientsInjury characteristicsSeverity scoreMortality ratioTraumatic injuryLower mortalityLogistic regressionPatientsRacial disparitiesMortalityInjurySurvivalReliability adjustment
Hashmi Z, Dimick J, Efron D, Haut E, Schneider E, Zafar S, Schwartz D, Cornwell E, Haider A. Reliability adjustment. Journal Of Trauma And Acute Care Surgery 2013, 75: 166-172. PMID: 23940864, PMCID: PMC3989535, DOI: 10.1097/ta.0b013e318298494f.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBenchmarkingCause of DeathDatabases, FactualFemaleHospital MortalityHumansInjury Severity ScoreMaleMiddle AgedOutcome Assessment, Health CareQuality ImprovementReproducibility of ResultsRisk AdjustmentSurvival AnalysisTrauma CentersUnited StatesWounds and InjuriesWounds, NonpenetratingWounds, PenetratingYoung AdultConceptsRisk-adjusted mortality ratesInjury Severity ScoreLow-volume centersMortality rateNational Trauma Data Bank 2010National Trauma Data BankReliability adjustmentHierarchical logistic regression modelingPatients 16 yearsRisk-adjusted mortalityTrauma Data BankNumber of patientsLogistic regression modelingHospital performance assessmentRisk adjustment methodsTrauma centerSeverity scoreVolume centersMortality ratioWorst quintileInterfacility variationCounting the lives lost: how many black trauma deaths are attributable to disparities?
Scott V, Hashmi Z, Schneider E, Hui X, Efron D, Cornwell E, Cooper L, Haider A. Counting the lives lost: how many black trauma deaths are attributable to disparities? Journal Of Surgical Research 2013, 184: 480-487. PMID: 23827793, PMCID: PMC5995316, DOI: 10.1016/j.jss.2013.04.080.Peer-Reviewed Original ResearchConceptsBlack patientsRisk of mortalityTrauma deathsRelative riskLevel IWhite patientsNational Trauma Data BankLevel II trauma centerRacial disparitiesTrauma center deathsTrauma Data BankWhite malesNumber of deathsTrauma centerExcess mortalityTrauma outcomesRetrospective analysisOutcome disparitiesPatientsExcess deathsMortalityDeathRiskInjuryBlunt