Featured Publications
Neural effects of controllability as a key dimension of stress exposure
Cohodes EM, Odriozola P, Mandell JD, Caballero C, McCauley S, Zacharek SJ, Hodges HR, Haberman JT, Smith M, Thomas J, Meisner OC, Ellis CT, Hartley CA, Gee DG. Neural effects of controllability as a key dimension of stress exposure. Development And Psychopathology 2022, 35: 218-227. PMID: 35034670, DOI: 10.1017/s0954579421001498.Peer-Reviewed Original ResearchConceptsDorsal anterior insulaRight dorsal anterior insulaUncontrollable stress conditionUncontrollable stressStress exposureSex-matched participantsStressor controllabilityInitial exposureFunctional magnetic resonance imaging (fMRI) acquisitionSubsequent stress exposureNeural effectsAnterior insulaYoung adultsSubsequent stressorsPatterns of activityCross-species evidenceNeural correlatesSubsequent exposureExposureNeural underpinningsPresent studyParticipantsMagnetic resonance imaging (MRI) acquisitionAdaptive responseFMRI analysis
2024
Developmental Differences in a Hippocampal-Cingulate Pathway Involved in Learned Safety Following Interpersonal Trauma Exposure
Kribakaran S, DeCross S, Odriozola P, McLaughlin K, Gee D. Developmental Differences in a Hippocampal-Cingulate Pathway Involved in Learned Safety Following Interpersonal Trauma Exposure. Journal Of The American Academy Of Child & Adolescent Psychiatry 2024 PMID: 39368629, DOI: 10.1016/j.jaac.2024.07.928.Peer-Reviewed Original ResearchSafety signal learningInterpersonal trauma exposureTrauma exposureFunctional connectivityHippocampal activityNeural correlatesConditioned safetyFunctional magnetic resonance imaging dataAnterior hippocampal activationDevelopment of psychopathologyAnterior cingulate subregionsTask-based functional magnetic resonance imaging dataExploratory analysisMagnetic resonance imaging dataMental health sequelaeAmygdala activationAge-related associationsAnterior hippocampalContingency awarenessPTSD symptomsInhibit fearAttenuating fearCingulate subregionsSignal learningFear reduction
2020
Comparing neural correlates of conditioned inhibition between children with and without anxiety disorders – A preliminary study
Harrewijn A, Kitt ER, Abend R, Matsumoto C, Odriozola P, Winkler AM, Leibenluft E, Pine DS, Gee DG. Comparing neural correlates of conditioned inhibition between children with and without anxiety disorders – A preliminary study. Behavioural Brain Research 2020, 399: 112994. PMID: 33160010, PMCID: PMC7855938, DOI: 10.1016/j.bbr.2020.112994.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPediatric anxiety disordersAnxiety disordersNeural correlatesHigher skin conductance responsesDorsal anterior cingulate cortexRight ventromedial prefrontal cortexVentromedial prefrontal cortexSkin conductance responsesReduced fear responsesAnterior cingulate cortexCurrent pilot studyThreat learningAnxious youthSafety cuesThreat cuesFear acquisitionVmPFC activityAversive soundSafety compoundCBT responseFear responsesNovel cuesConductance responsesPrefrontal cortex