Modeling seizure networks in neuron-glia cultures using microelectrode arrays
Boddeti U, Langbein J, McAfee D, Altshuler M, Bachani M, Zaveri H, Spencer D, Zaghloul K, Ksendzovsky A. Modeling seizure networks in neuron-glia cultures using microelectrode arrays. Frontiers In Network Physiology 2024, 4: 1441345. PMID: 39290793, PMCID: PMC11405204, DOI: 10.3389/fnetp.2024.1441345.Peer-Reviewed Original ResearchNetwork changesSeizure networkSeizure modelsDays of chronic treatmentDimensionality reductionNetwork developmentDrug-resistant epilepsyNeuron-glia culturesMean firing rateNetworkTreatment failureChronic treatmentMicroelectrode arraysResection surgeryRetrospective studyFiring rateSeizuresExperience seizuresNeurological disordersOptimized Multilayer Perceptron for Sensorimotor Functional Mapping Based on a Few Minutes of Intracranial Electroencephalogram Data
Iktimal A, Spencer D, Alkawadri R. Optimized Multilayer Perceptron for Sensorimotor Functional Mapping Based on a Few Minutes of Intracranial Electroencephalogram Data. Annals Of Neurology 2024, 96: 187-193. PMID: 38506405, DOI: 10.1002/ana.26915.Peer-Reviewed Original ResearchMultilayer perceptronTanh activation functionArea under the curveMultilayer Perceptron performanceOptimal multilayer perceptronImbalanced dataF1 scoreFeature extensionNeural networkActivation functionElectroencephalogram-dataSensorimotor cortexIntractable epilepsy patientsPerceptronCentral sulcusCross-validationAnterior lipEpilepsy patientsGaussian distribution functionFunctional mappingNetworkMetrics