2015
Voltage‐dependent K+ currents contribute to heterogeneity of olfactory ensheathing cells
Rela L, Piantanida AP, Bordey A, Greer CA. Voltage‐dependent K+ currents contribute to heterogeneity of olfactory ensheathing cells. Glia 2015, 63: 1646-1659. PMID: 25856239, PMCID: PMC4506201, DOI: 10.1002/glia.22834.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell MembraneConnexin 43FemaleGap JunctionsImmunohistochemistryMaleMiceMyelin SheathOlfactory NervePatch-Clamp TechniquesPotassiumPotassium Channels, Voltage-GatedTissue Culture TechniquesConceptsGlial cellsOlfactory nerveAxon growthVoltage-dependent potassium currentsOlfactory Ensheathing CellsSite of injuryGap junction couplingPotassium currentPotassium channelsJunction couplingInward rectifierNerveRectifier channelsCellsPhysiological propertiesLimited knowledgeInjuryOECsMembrane propertiesFascicles
1999
Differential Inhibition of Glial K+ Currents by 4-AP
Bordey A, Sontheimer H. Differential Inhibition of Glial K+ Currents by 4-AP. Journal Of Neurophysiology 1999, 82: 3476-3487. PMID: 10601476, DOI: 10.1152/jn.1999.82.6.3476.Peer-Reviewed Original ResearchMeSH Keywords4-AminopyridineAction PotentialsAnimalsAstrocytesCells, CulturedDelayed Rectifier Potassium ChannelsElectrophysiologyLarge-Conductance Calcium-Activated Potassium ChannelsNeurogliaPatch-Clamp TechniquesPotassium Channel BlockersPotassium ChannelsPotassium Channels, Calcium-ActivatedPotassium Channels, Inwardly RectifyingPotassium Channels, Voltage-GatedRatsRats, Sprague-DawleySpinal CordTetraethylammoniumConceptsAcute spinal cord slicesSpinal cord slicesConcentration-dependent blockPotassium channel typesType currentsDose-dependent inhibitorNeuronal action potentialsCord slicesSpinal cordChannel blockersEpileptiform dischargesBrain slicesAction potentialsHomeostatic functionsA-currentAstrocytesDifferential inhibitionRepolarizationMembrane potentialChannel typesSlicesBlockersGlialCord
1998
Electrophysiological Properties of Human Astrocytic Tumor Cells In Situ: Enigma of Spiking Glial Cells
Bordey A, Sontheimer H. Electrophysiological Properties of Human Astrocytic Tumor Cells In Situ: Enigma of Spiking Glial Cells. Journal Of Neurophysiology 1998, 79: 2782-2793. PMID: 9582244, DOI: 10.1152/jn.1998.79.5.2782.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAstrocytesAstrocytomaBrain NeoplasmsCarcinomaCell DifferentiationChildChoroid Plexus NeoplasmsDelayed Rectifier Potassium ChannelsHumansIon TransportNeoplasm ProteinsNeoplastic Stem CellsNerve Tissue ProteinsPatch-Clamp TechniquesPotassiumPotassium Channel BlockersPotassium ChannelsPotassium Channels, Inwardly RectifyingPotassium Channels, Voltage-GatedSodium Channel BlockersSodium ChannelsSpinal CordTetraethylammoniumTetrodotoxinConceptsAstrocytoma cellsTumor cellsGlial cellsWhole-cell patch-clamp recordingsCell patch-clamp recordingsAction potential-like responsesOlder pediatric patientsSpinal cord astrocytesHuman astrocytic tumor cellsSensitive sodium currentsGroup of tumorsLow-grade astrocytomasPatch-clamp recordingsOutward potassium currentGlial tumor cellsAstrocytic tumor cellsGeneration of spikesHigh input resistancePeritumoral astrocytesPediatric patientsMicroM Ba2Pilocytic astrocytomaPotassium currentAstrocytesElectrophysiological properties