Hang Zhou, PhD
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About
Titles
Assistant Professor of Psychiatry, and of Biomedical Informatics and Data Science
Biography
Hang Zhou, PhD, is Assistant Professor of Psychiatry and of Biomedical Informatics and Data Science, Yale School of Medicine. Dr. Zhou has a broad background in computational biology and psychiatric genetics with rich experience in genomic data analyses and inferences. The main research interest is to identify novel genetic risks and explore the biological etiology for alcohol use disorder, substance use disorders and the relationship with comorbidities. Dr. Zhou’s lab will continue research on addiction, sex differences and relationship between alcohol and cancers using large-scale human genetic data (SNP array, WES and whole genome sequencing), exploring Machine Learning and leveraging brain imaging data to investigate the mechanisms through broad collaborations.
Appointments
Psychiatry
Assistant ProfessorPrimaryBiomedical Informatics & Data Science
Assistant ProfessorSecondary
Other Departments & Organizations
- Biomedical Informatics & Data Science
- Center for Brain & Mind Health
- Lab - Psychiatry - Zhou, Hang
- Psychiatry
Education & Training
- Associate Research Scientist
- Yale School of Medicine (2021)
- Postdoctoral Associate
- Yale School of Medicine (2018)
- PhD
- CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences (2015)
- BSc
- Shanghai Jiao Tong University (2009)
Research
Academic Achievements and Community Involvement
Links & Media
Media
Million Veteran Program phase1 GWAS of alcohol use disorder and AUDIT-C (Kranzler*, Zhou*, Kember*, Nature Communications, 2019)
GWAS of AUD and AUDIT-C in 274,424 individuals from MVP. EA: European American, AA: African American, LA: Hispanic or Latino, EAA: East Asian American, SAA: South Asian American.SNP-based heritability of AUD and AUDIT-C, heritability enrichment and genetic correlations with other traits.
AUD differs from AUDIT-C genetically.Principal component analyses of MVP subjects and 1000 Genomes Project.
Outliers were removed in MVP after 2nd round of PCA.Missing diversity in genetic studies of alcohol-related traits. (Unpublished)
More data is needed, especially in non-European populations.
News
- June 12, 2024
YSM, VA Researchers Complete First Genome-Wide Association Study of Epiretinal Membrane
- April 05, 2024Source: Molecular Psychiatry
Genetic Influences and Causal Pathways Shared Between Cannabis Use Disorder and Other Substance Use Traits
- December 07, 2023
VA/Yale Researchers Lead Multi-ancestry Study of Genetics of Problematic Alcohol Use
- September 22, 2023Source: Psychological Medicine
In Study of Veterans, Positive Personality Traits Moderate Persistent High Alcohol Consumption