Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma
Jacobson B, Sadiq A, Tang S, Jay-Dixon J, Patel M, Drees J, Sorenson B, Russell S, Kratzke R. Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma. Oncotarget 2017, 5: 63096-63109. PMID: 28968974, PMCID: PMC5609906, DOI: 10.18632/oncotarget.18656.Peer-Reviewed Original ResearchMV-EdmMalignant mesotheliomaMesothelioma cellsLysis of cancer cellsOncolytic viral efficacyMeasles virus infectionEdmonston vaccine strainNumerous tumor typesRepression of cap-dependent translationTumor cell selectivityExpression of eIF4EOncolytic activityApoptotic cell deathTumor typesPoor prognosisReceptor CD46IGF-INectin-4Clinical trialsViral efficacyNon-cancerous cellsMesotheliomaCancer cellsVirus infectionMeasles virus
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